O contributo da tomografia computorizada de perfusão no acidente vascular cerebral.

Multisection computed tomography (MSCT) was introduced in 1998 and improved neuroimaging quality, in particular concerning acute stroke. Previously, non-enhanced CT was used not only to detect early stroke signs, but also to exclude hemorrhage and non-vascular pathology responsible for the acute neu...

Full description

Bibliographic Details
Main Authors: Leonor Lopes, Rita Sousa, Joana Ruivo, Sofia Reimão, Paulo Sequeira, Jorge Campos
Format: Article
Language:English
Published: Ordem dos Médicos 2006-12-01
Series:Acta Médica Portuguesa
Online Access:https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/941
Description
Summary:Multisection computed tomography (MSCT) was introduced in 1998 and improved neuroimaging quality, in particular concerning acute stroke. Previously, non-enhanced CT was used not only to detect early stroke signs, but also to exclude hemorrhage and non-vascular pathology responsible for the acute neurological deficit. Nowadays, using Perfusion CT (PCT) it is possible to obtain a functional study of the cerebral hemodinamics after injection of a fast bolus of contrast. Multi-voxel analysis of the time-attenuation curves delivers colour maps of Cerebral Blood Flow (CBF), Mean Time Transit (MTT) and Cerebral Blood Flow (CBF). Based on specific patterns of hemodinamic changes it is possible to differentiate between irreversible and reversible brain damage--"tissue at risk", which is essential for choosing an appropriate therapy. The authors will discuss data acquisition, post-processing and image interpretation and analysis starting from two clinical examples.
ISSN:0870-399X
1646-0758