Layer‐Specific BTX‐A Delivery to the Gastric Muscularis Achieves Effective Weight Control and Metabolic Improvement

Layer‐Specific BTX‐A Delivery to the Gastric Muscularis Achieves Effective Weight Control and Metabolic Improvement

Abstract The rising incidence of health‐endangering obesity constantly calls for more effective treatments. Gastric intramural injection of botulinum neurotoxin A (BTX‐A) as a new modality carries great promise yet inconsistent therapeutic efficacy. A layer‐specific delivery strategy enabled by diss...

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Bibliographic Details
Main Authors: Siqi Wang, Yuqiong Wang, Long Lin, Zongjie Li, Fengyi Liu, Long Zhu, Jie Chen, Nianrong Zhang, Xinyu Cao, Sunman Ran, Genzheng Liu, Peng Gao, Weiliang Sun, Liang Peng, Jian Zhuang, Hua Meng
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Advanced Science
Subjects:
botulinum neurotoxin A
glucagon‐like peptide‐1
microneedle patch
obesity
precise delivery
Online Access:https://doi.org/10.1002/advs.202300822

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