Relative quantification of deuterated omega-3 and -6 fatty acids and their lipid turnover in PC12 cell membranes using TOF-SIMS

Relative quantification of deuterated omega-3 and -6 fatty acids and their lipid turnover in PC12 cell membranes using TOF-SIMS

Understanding FA metabolism and lipid synthesis requires a lot of information about which FAs and lipids are formed within the cells. We focused on the use of deuterated substrates of 100 μM α-linolenic acid and linoleic acid to determine the relative amounts of their converted PUFAs and specific ph...

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Bibliographic Details
Main Authors: Mai H. Philipsen, Sanna Sämfors, Per Malmberg, Andrew G. Ewing
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Journal of Lipid Research
Subjects:
time-of-flight secondary ion mass spectrometry
phospholipids
α-linolenic acid
linoleic acid
lipid turnover
fatty acids
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752030910X

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