<italic toggle="yes">Salmonella</italic> Reprograms Nucleotide Metabolism in Its Adaptation to Nitrosative Stress

<italic toggle="yes">Salmonella</italic> Reprograms Nucleotide Metabolism in Its Adaptation to Nitrosative Stress

ABSTRACT The adaptations that protect pathogenic microorganisms against the cytotoxicity of nitric oxide (NO) engendered in the immune response are incompletely understood. We show here that salmonellae experiencing nitrosative stress suffer dramatic losses of the nucleoside triphosphates ATP, GTP,...

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Bibliographic Details
Main Authors: Liam F. Fitzsimmons, Lin Liu, Ju-Sim Kim, Jessica Jones-Carson, Andrés Vázquez-Torres
Format: Article
Language:English
Published: American Society for Microbiology 2018-03-01
Series:mBio
Subjects:
Salmonella
adaptive resistance
animal models
cellular redox status
guanosine tetraphosphate
nitric oxide
Online Access:https://journals.asm.org/doi/10.1128/mBio.00211-18

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