Homocysteine – relation to hypertension, age and smoking in patients with newly diagnosed essential hypertension
Introduction. An elevated circulating concentration of homocysteine is associated with an increased risk of coronary, cerebral, and peripheral vascular disease. The purpose of this study was to determine the concentrations of homocysteine in the patients with newly diagnosed essential hypertension a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Poznan University of Medical Sciences
2015-06-01
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| Series: | Journal of Medical Science |
| Subjects: | |
| Online Access: | https://jms.ump.edu.pl/index.php/JMS/article/view/22 |
| _version_ | 1818715567492694016 |
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| author | Katarzyna Korzeniowska Artur Cieślewicz Ewa Chmara Anna Jabłecka |
| author_facet | Katarzyna Korzeniowska Artur Cieślewicz Ewa Chmara Anna Jabłecka |
| author_sort | Katarzyna Korzeniowska |
| collection | DOAJ |
| description | Introduction. An elevated circulating concentration of homocysteine is associated with an increased risk of coronary, cerebral, and peripheral vascular disease. The purpose of this study was to determine the concentrations of homocysteine in the patients with newly diagnosed essential hypertension and healthy subjects and to analyze the correlation between homocysteine level and the other parameters (age, blood pressure, smoking).
Material and methods. The study group consisted of 18 patients with essential hypertension, 4 women and 14 men (mean age 43 ± 16 years) and 15 healthy volunteers, 8 women and 7 men (mean age 47 ± 10 years). Serum homocysteine was analyzed by FPIA method (Fluorescence Polarization Immunoassay).
Results. The patients with essential hypertension had significantly higher homocysteine concentration compared to control group. No correlation was observed between homocysteine levels and age, diastolic, systolic blood pressure in subjects with essential hypertension. In healthy volunteers, only a correlation between age and homocysteine concentration was found. |
| first_indexed | 2024-12-17T19:05:25Z |
| format | Article |
| id | doaj.art-e705f9f1cd6e40f082604bdfbf7ce07b |
| institution | Directory Open Access Journal |
| issn | 2353-9798 2353-9801 |
| language | English |
| last_indexed | 2024-12-17T19:05:25Z |
| publishDate | 2015-06-01 |
| publisher | Poznan University of Medical Sciences |
| record_format | Article |
| series | Journal of Medical Science |
| spelling | doaj.art-e705f9f1cd6e40f082604bdfbf7ce07b2022-12-21T21:36:00ZengPoznan University of Medical SciencesJournal of Medical Science2353-97982353-98012015-06-0184210.20883/medical.e22Homocysteine – relation to hypertension, age and smoking in patients with newly diagnosed essential hypertensionKatarzyna Korzeniowska0Artur Cieślewicz1Ewa Chmara2Anna Jabłecka3Department of Clinical Pharmacology, Poznan University of Medical Sciences, PolandDepartment of Clinical Pharmacology, Poznan University of Medical Sciences, PolandDepartment of Clinical Pharmacology, Poznan University of Medical Sciences, PolandDepartment of Clinical Pharmacology, Poznan University of Medical Sciences, PolandIntroduction. An elevated circulating concentration of homocysteine is associated with an increased risk of coronary, cerebral, and peripheral vascular disease. The purpose of this study was to determine the concentrations of homocysteine in the patients with newly diagnosed essential hypertension and healthy subjects and to analyze the correlation between homocysteine level and the other parameters (age, blood pressure, smoking). Material and methods. The study group consisted of 18 patients with essential hypertension, 4 women and 14 men (mean age 43 ± 16 years) and 15 healthy volunteers, 8 women and 7 men (mean age 47 ± 10 years). Serum homocysteine was analyzed by FPIA method (Fluorescence Polarization Immunoassay). Results. The patients with essential hypertension had significantly higher homocysteine concentration compared to control group. No correlation was observed between homocysteine levels and age, diastolic, systolic blood pressure in subjects with essential hypertension. In healthy volunteers, only a correlation between age and homocysteine concentration was found.https://jms.ump.edu.pl/index.php/JMS/article/view/22homocysteinehypertensionblood pressure |
| spellingShingle | Katarzyna Korzeniowska Artur Cieślewicz Ewa Chmara Anna Jabłecka Homocysteine – relation to hypertension, age and smoking in patients with newly diagnosed essential hypertension Journal of Medical Science homocysteine hypertension blood pressure |
| title | Homocysteine – relation to hypertension, age and smoking in patients with newly diagnosed essential hypertension |
| title_full | Homocysteine – relation to hypertension, age and smoking in patients with newly diagnosed essential hypertension |
| title_fullStr | Homocysteine – relation to hypertension, age and smoking in patients with newly diagnosed essential hypertension |
| title_full_unstemmed | Homocysteine – relation to hypertension, age and smoking in patients with newly diagnosed essential hypertension |
| title_short | Homocysteine – relation to hypertension, age and smoking in patients with newly diagnosed essential hypertension |
| title_sort | homocysteine relation to hypertension age and smoking in patients with newly diagnosed essential hypertension |
| topic | homocysteine hypertension blood pressure |
| url | https://jms.ump.edu.pl/index.php/JMS/article/view/22 |
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