HIV reservoir quantification using cross-subtype multiplex ddPCR

HIV reservoir quantification using cross-subtype multiplex ddPCR

Summary: A major barrier to conducting HIV cure research in populations with the highest HIV burden is the lack of an accurate assay to quantify the replication-competent reservoir across the dominant global HIV-1 subtypes. Here, we modify a subtype B HIV-1 assay that quantifies both intact and defe...

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Bibliographic Details
Main Authors: Noah A.J. Cassidy, Carolyn S. Fish, Claire N. Levy, Pavitra Roychoudhury, Daniel B. Reeves, Sean M. Hughes, Joshua T. Schiffer, Sarah Benki-Nugent, Grace John-Stewart, Dalton Wamalwa, Keith R. Jerome, Julie Overbaugh, Florian Hladik, Dara A. Lehman
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:iScience
Subjects:
Virology
Genotyping
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221015856

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