Patients with cluster headache show signs of insomnia and sleep related stress: results from an actigraphy and self-assessed sleep study
Abstract Background Cluster headache (CH) is a primary headache disorder which is characterized by circadian timing of headache attacks, usually at nighttime, in around two thirds of patients. Patients with CH often report sleep difficulties, though it is unknown whether this is a cause or a consequ...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-08-01
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| Series: | The Journal of Headache and Pain |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s10194-023-01650-w |
| _version_ | 1797452070723256320 |
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| author | Caroline Ran Felicia Jennysdotter Olofsgård Anna Steinberg Christina Sjöstrand Elisabet Waldenlind Anna Dahlgren Andrea Carmine Belin |
| author_facet | Caroline Ran Felicia Jennysdotter Olofsgård Anna Steinberg Christina Sjöstrand Elisabet Waldenlind Anna Dahlgren Andrea Carmine Belin |
| author_sort | Caroline Ran |
| collection | DOAJ |
| description | Abstract Background Cluster headache (CH) is a primary headache disorder which is characterized by circadian timing of headache attacks, usually at nighttime, in around two thirds of patients. Patients with CH often report sleep difficulties, though it is unknown whether this is a cause or a consequence of nightly headache attacks. Objective In this case-control study we have assessed sleep quality in study participants with CH in cluster bout respectively in remission, compared to a control group of neurologically healthy individuals to investigate the potential connection between sleep and CH. Methods Fifty study participants with CH and 42 controls were recruited for sleep assessment. Sleep was recorded using MotionWatch 8 actigraphs (CamNTech) for a period of two weeks. Study participants were instructed to wear the unit during rest and sleep and to fill out a sleep diary daily through the two-weeks period. Results Results from actigraphy recordings and sleep diaries suggested that patients with CH spend longer time in bed than controls (CH 8.1 hours vs. Controls 7.7 hours, p=0.03), but do not sleep more than controls (CH 6.7 hours vs. controls 6.5 hours, p=0.3). In addition, CH patients reported increased sleep latency (p=0.003), particularly during, but not restricted to, cluster bouts. Study participants with CH further reported higher levels of stress at bedtime (p=0.01), and they felt less well rested than controls (p=0.001). Conclusion Our analysis suggests that sleep is negatively affected in CH both in cluster bout and in remission, manifesting in symptoms consistent with insomnia such as prolonged sleep latency and increased time in bed. |
| first_indexed | 2024-03-09T15:02:28Z |
| format | Article |
| id | doaj.art-e70786be39754ba6a4d8fafdba55333b |
| institution | Directory Open Access Journal |
| issn | 1129-2377 |
| language | English |
| last_indexed | 2024-03-09T15:02:28Z |
| publishDate | 2023-08-01 |
| publisher | BMC |
| record_format | Article |
| series | The Journal of Headache and Pain |
| spelling | doaj.art-e70786be39754ba6a4d8fafdba55333b2023-11-26T13:50:45ZengBMCThe Journal of Headache and Pain1129-23772023-08-0124111210.1186/s10194-023-01650-wPatients with cluster headache show signs of insomnia and sleep related stress: results from an actigraphy and self-assessed sleep studyCaroline Ran0Felicia Jennysdotter Olofsgård1Anna Steinberg2Christina Sjöstrand3Elisabet Waldenlind4Anna Dahlgren5Andrea Carmine Belin6Centre for Cluster Headache, Department of Neuroscience, Karolinska InstitutetCentre for Cluster Headache, Department of Neuroscience, Karolinska InstitutetDepartment of Clinical Neuroscience, Karolinska InstitutetDepartment of Clinical Neuroscience, Karolinska InstitutetDepartment of Clinical Neuroscience, Karolinska InstitutetDepartment of Clinical Neuroscience, Karolinska InstitutetCentre for Cluster Headache, Department of Neuroscience, Karolinska InstitutetAbstract Background Cluster headache (CH) is a primary headache disorder which is characterized by circadian timing of headache attacks, usually at nighttime, in around two thirds of patients. Patients with CH often report sleep difficulties, though it is unknown whether this is a cause or a consequence of nightly headache attacks. Objective In this case-control study we have assessed sleep quality in study participants with CH in cluster bout respectively in remission, compared to a control group of neurologically healthy individuals to investigate the potential connection between sleep and CH. Methods Fifty study participants with CH and 42 controls were recruited for sleep assessment. Sleep was recorded using MotionWatch 8 actigraphs (CamNTech) for a period of two weeks. Study participants were instructed to wear the unit during rest and sleep and to fill out a sleep diary daily through the two-weeks period. Results Results from actigraphy recordings and sleep diaries suggested that patients with CH spend longer time in bed than controls (CH 8.1 hours vs. Controls 7.7 hours, p=0.03), but do not sleep more than controls (CH 6.7 hours vs. controls 6.5 hours, p=0.3). In addition, CH patients reported increased sleep latency (p=0.003), particularly during, but not restricted to, cluster bouts. Study participants with CH further reported higher levels of stress at bedtime (p=0.01), and they felt less well rested than controls (p=0.001). Conclusion Our analysis suggests that sleep is negatively affected in CH both in cluster bout and in remission, manifesting in symptoms consistent with insomnia such as prolonged sleep latency and increased time in bed.https://doi.org/10.1186/s10194-023-01650-wSleepSleep disturbanceHeadachePainCircadian rhythm |
| spellingShingle | Caroline Ran Felicia Jennysdotter Olofsgård Anna Steinberg Christina Sjöstrand Elisabet Waldenlind Anna Dahlgren Andrea Carmine Belin Patients with cluster headache show signs of insomnia and sleep related stress: results from an actigraphy and self-assessed sleep study The Journal of Headache and Pain Sleep Sleep disturbance Headache Pain Circadian rhythm |
| title | Patients with cluster headache show signs of insomnia and sleep related stress: results from an actigraphy and self-assessed sleep study |
| title_full | Patients with cluster headache show signs of insomnia and sleep related stress: results from an actigraphy and self-assessed sleep study |
| title_fullStr | Patients with cluster headache show signs of insomnia and sleep related stress: results from an actigraphy and self-assessed sleep study |
| title_full_unstemmed | Patients with cluster headache show signs of insomnia and sleep related stress: results from an actigraphy and self-assessed sleep study |
| title_short | Patients with cluster headache show signs of insomnia and sleep related stress: results from an actigraphy and self-assessed sleep study |
| title_sort | patients with cluster headache show signs of insomnia and sleep related stress results from an actigraphy and self assessed sleep study |
| topic | Sleep Sleep disturbance Headache Pain Circadian rhythm |
| url | https://doi.org/10.1186/s10194-023-01650-w |
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