Identification of Anti-TNFα VNAR Single Domain Antibodies from Whitespotted Bambooshark (<i>Chiloscyllium plagiosum</i>)

Identification of Anti-TNFα VNAR Single Domain Antibodies from Whitespotted Bambooshark (<i>Chiloscyllium plagiosum</i>)

Tumor necrosis factor α (TNFα), an important clinical testing factor and drug target, can trigger serious autoimmune diseases and inflammation. Thus, the TNFα antibodies have great potential application in diagnostics and therapy fields. The variable binding domain of IgNAR (VNAR), the shark single...

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Bibliographic Details
Main Authors: Linfei Zhao, Mingliang Chen, Xiaona Wang, Shoukai Kang, Weiwei Xue, Zengpeng Li
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Marine Drugs
Subjects:
whitespotted bambooshark
IgNAR
VNAR
single domain antibody
TNFα
Online Access:https://www.mdpi.com/1660-3397/20/5/307

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