Hepatitis E seroprevalence and associated factors in rural settlers in Central Brazil

Abstract INTRODUCTION: Prevalence of hepatitis E virus (HEV) infection and associated factors were investigated in rural settlements in Central Brazil. METHODS: A total of 464 settlers were interviewed, and serum samples were tested for anti-HEV IgG/IgM. Positive samples were tested for HEV RNA....

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Main Authors: Nara Rubia de Freitas, Sheila Araújo Teles, Karlla Antonieta Amorim Caetano, Marcos Andre de Matos, Megmar Aparecida dos Santos Carneiro, Noemi Rovaris Gardinali, Marcelo Alves Pinto, Regina Maria Bringel Martins
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT)
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822017000500675&lng=en&tlng=en
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author Nara Rubia de Freitas
Sheila Araújo Teles
Karlla Antonieta Amorim Caetano
Marcos Andre de Matos
Megmar Aparecida dos Santos Carneiro
Noemi Rovaris Gardinali
Marcelo Alves Pinto
Regina Maria Bringel Martins
author_facet Nara Rubia de Freitas
Sheila Araújo Teles
Karlla Antonieta Amorim Caetano
Marcos Andre de Matos
Megmar Aparecida dos Santos Carneiro
Noemi Rovaris Gardinali
Marcelo Alves Pinto
Regina Maria Bringel Martins
author_sort Nara Rubia de Freitas
collection DOAJ
description Abstract INTRODUCTION: Prevalence of hepatitis E virus (HEV) infection and associated factors were investigated in rural settlements in Central Brazil. METHODS: A total of 464 settlers were interviewed, and serum samples were tested for anti-HEV IgG/IgM. Positive samples were tested for HEV RNA. RESULTS: Sixteen participants (3.4%; 95% CI 2.0-5.7) were positive for anti-HEV IgG. None was positive for anti-HEV IgM. HEV RNA was not detected. Dwelling in a rural settlement for >5 years was associated with HEV seropositivity. CONCLUSIONS: The results revealed the absence of acute infection and a low prevalence of previous exposure to HEV.
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spelling doaj.art-e70b3248ca564635b940c0f30b399f072022-12-22T00:14:10ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-984950567567910.1590/0037-8682-0105-2017S0037-86822017000500675Hepatitis E seroprevalence and associated factors in rural settlers in Central BrazilNara Rubia de FreitasSheila Araújo TelesKarlla Antonieta Amorim CaetanoMarcos Andre de MatosMegmar Aparecida dos Santos CarneiroNoemi Rovaris GardinaliMarcelo Alves PintoRegina Maria Bringel MartinsAbstract INTRODUCTION: Prevalence of hepatitis E virus (HEV) infection and associated factors were investigated in rural settlements in Central Brazil. METHODS: A total of 464 settlers were interviewed, and serum samples were tested for anti-HEV IgG/IgM. Positive samples were tested for HEV RNA. RESULTS: Sixteen participants (3.4%; 95% CI 2.0-5.7) were positive for anti-HEV IgG. None was positive for anti-HEV IgM. HEV RNA was not detected. Dwelling in a rural settlement for >5 years was associated with HEV seropositivity. CONCLUSIONS: The results revealed the absence of acute infection and a low prevalence of previous exposure to HEV.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822017000500675&lng=en&tlng=enHepatitis E vírusEpidemiologyRural settlement
spellingShingle Nara Rubia de Freitas
Sheila Araújo Teles
Karlla Antonieta Amorim Caetano
Marcos Andre de Matos
Megmar Aparecida dos Santos Carneiro
Noemi Rovaris Gardinali
Marcelo Alves Pinto
Regina Maria Bringel Martins
Hepatitis E seroprevalence and associated factors in rural settlers in Central Brazil
Revista da Sociedade Brasileira de Medicina Tropical
Hepatitis E vírus
Epidemiology
Rural settlement
title Hepatitis E seroprevalence and associated factors in rural settlers in Central Brazil
title_full Hepatitis E seroprevalence and associated factors in rural settlers in Central Brazil
title_fullStr Hepatitis E seroprevalence and associated factors in rural settlers in Central Brazil
title_full_unstemmed Hepatitis E seroprevalence and associated factors in rural settlers in Central Brazil
title_short Hepatitis E seroprevalence and associated factors in rural settlers in Central Brazil
title_sort hepatitis e seroprevalence and associated factors in rural settlers in central brazil
topic Hepatitis E vírus
Epidemiology
Rural settlement
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822017000500675&lng=en&tlng=en
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