A Novel Human Antibody, HF, against HER2/erb-B2 Obtained by a Computer-Aided Antibody Design Method

A Novel Human Antibody, HF, against HER2/erb-B2 Obtained by a Computer-Aided Antibody Design Method

Fully human antibodies have minimal immunogenicity and safety profiles. At present, most potential antibody drugs in clinical trials are humanized or fully human. Human antibodies are mostly generated using the phage display method (in vitro) or by transgenic mice (in vivo); other methods include B...

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Bibliographic Details
Main Authors: Chunxia Qiao, Ming Lv, Xinying Li, Xiaoling Lang, Shouqin Lv, Mian Long, Yan Li, Shusheng Geng, Zhou Lin, Beifen Shen, Jiannan Feng
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Engineering
Subjects:
HER2/erb-B2
Human antibody
Computer-aided design
Online Access:http://www.sciencedirect.com/science/article/pii/S2095809921003829

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