Annexin A1 Regulates NLRP3 Inflammasome Activation and Modifies Lipid Release Profile in Isolated Peritoneal Macrophages

Annexin A1 Regulates NLRP3 Inflammasome Activation and Modifies Lipid Release Profile in Isolated Peritoneal Macrophages

Annexin A1 (AnxA1) is a potent anti-inflammatory protein that downregulates proinflammatory cytokine release. This study evaluated the role of AnxA1 in the regulation of NLRP3 inflammasome activation and lipid release by starch-elicited murine peritoneal macrophages. C57bl/6 wild-type (WT) and AnxA1...

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Bibliographic Details
Main Authors: José Marcos Sanches, Laura Migliari Branco, Gustavo Henrique Bueno Duarte, Sonia Maria Oliani, Karina Ramalho Bortoluci, Vanessa Moreira, Cristiane Damas Gil
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
inflammation
nigericin
pyroptosis
mass spectrometry
lipidomics
Online Access:https://www.mdpi.com/2073-4409/9/4/926

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