Water Borne Hepatitis A and Hepatitis E in Malwa Region of Punjab,India
Introduction: Hepatitis-A virus infection (HAV) and Hepatitis E virus infection (HEV) are faecally contaminated water borne infection of great public interest in developing countries. HAV has a world-wide distribution and affects infant and young children in developing countries and its epidemic...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2013-10-01
|
| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/3459/16-%205966%20E(V)_PF1(V)_F(DK)_PF2(Bo_PVP)_u_PF3(PP)_u(P).pdf |
| Summary: | Introduction: Hepatitis-A virus infection (HAV) and Hepatitis
E virus infection (HEV) are faecally contaminated water borne
infection of great public interest in developing countries. HAV
has a world-wide distribution and affects infant and young
children in developing countries and its epidemics are not very
common. HEV is restricted to tropical countries and affects
older children and young adults and its epidemics are common.
Studies suggested that HEV is etiologically responsible for
10%–95% of admitted cases of hepatitis. Exposure rates over
a period of time are different in different parts of the country and
in different socio-economic groups.
Aim of the study 1. To study the prevalence of HAV and HEV
in the outbreak of hepatitis in certain areas of Malwa region of
Punjab, India.
2. To determine the age specific prevalence rates of HAV and
HEV.
3. To determine any change in the epidemiology of these
infections.
Material and Methods: This study was conducted in the
Department of Microbiology in GGMC and Hospital Faridkot,
A leading Tertiary care hospital and the major referral centre of
malwa region of Punjab,India.
Collection and Serological Tests: 1.Venous blood samples of
patients of acute hepatitis were taken.
2.Relavent information regarding their Age, Sex Education,
Socio-economic status, personal and community hygiene were
recorded. All of the sera were screened for IgM Antibody to HEV
and HAV using IgM capture ELISA Kit (ASIA-LION Biotechnology
for HEV and GENERAL BIOLOGICAL CORPORATION for HAV )
in accordance with the manufacturer’s instructions.
Result and Conclusion : 1.The outbreak was due to hepatitis A
&E virus(HEV predominating resulting from fecal contamination
of drinking water). 2.Hepatitis E is more widely prevalent 3.There
is a change in the epidemiology of HAV so,more cases are seen
in age group of more than 20 years. |
|---|---|
| ISSN: | 2249-782X 0973-709X |