Generation of a PPM1A-deficient human induced pluripotent stem cell line using CRISPR-Cas9 technology

PPM1A is a member of the serine/threonine protein phosphatase family. It can bind to a variety of proteins to dephosphorylate them, and extensively regulates many life activities such as cell growth, cell stress, immune response, and tumor formation. Here we constructed a human induced pluripotent s...

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Bibliographic Details
Main Authors: Xinrui Guo, Kui Zhao, Yanqi Zhang, Tiancheng Zhou, Guangjin Pan
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506124001181