CircVAPA promotes small cell lung cancer progression by modulating the miR-377-3p and miR-494-3p/IGF1R/AKT axis

CircVAPA promotes small cell lung cancer progression by modulating the miR-377-3p and miR-494-3p/IGF1R/AKT axis

Abstract Background Multiple lines of evidence have demonstrated that circular RNAs (circRNAs) play oncogenic or tumor-suppressive roles in various human cancers. Nevertheless, the biological functions of circRNAs in small cell lung cancer (SCLC) are still elusive. Methods CircVAPA (annotated as hsa...

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Bibliographic Details
Main Authors: Jinghan Hua, Xiaolin Wang, Liying Ma, Jingxin Li, Guozhen Cao, Shaobo Zhang, Wenchu Lin
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Molecular Cancer
Subjects:
CircVAPA
SCLC
Progression
miR-377-3p
miR-494-3p
IGF1R
Online Access:https://doi.org/10.1186/s12943-022-01595-9

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