The Effect of Age on Clinical and Laboratory Parameters in Reproductive Age Women with Endometrial Polyps
OBJECTIVE: To compare clinical and laboratory parameters in middle and advanced reproductive age women with endometrial polyps. STUDY DESIGN: We designed a retrospective study among reproductive age women who were managed at our clinic with the diagnosis of endometrial polyps. Thirty seven women old...
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| Format: | Article |
| Language: | English |
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Medical Network
2016-05-01
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| Series: | Gynecology Obstetrics & Reproductive Medicine |
| Subjects: | |
| Online Access: | http://gorm.com.tr/index.php/GORM/article/view/163 |
| _version_ | 1797906781030055936 |
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| author | Aytekin Tokmak Ebru Ersoy Ali Özgür Ersoy Esra Yaşar Çelik Ali İrfan Güzel Mustafa Uğur |
| author_facet | Aytekin Tokmak Ebru Ersoy Ali Özgür Ersoy Esra Yaşar Çelik Ali İrfan Güzel Mustafa Uğur |
| author_sort | Aytekin Tokmak |
| collection | DOAJ |
| description | OBJECTIVE: To compare clinical and laboratory parameters in middle and advanced reproductive age women with endometrial polyps.
STUDY DESIGN: We designed a retrospective study among reproductive age women who were managed at our clinic with the diagnosis of endometrial polyps. Thirty seven women older than 40 years of age (study group), and 113 women younger than 40 years (control group) were compared in terms of various clinical and laboratory parameters including age, body mass index (BMI), gravidity, parity, abortion, basal hormone levels, tumor markers, complete blood count values, smoking status, presence of polycystic ovary syndrome (PCOS), infertility status, co-morbidities, and number and size of endometrial
polyps.
RESULTS: The mean age of patients in the study and control groups were 45.2±3.5 and 30.6±4.9 years, respectively (p<0.001). The median BMI, gravidity, parity and abortion were significantly higher in study group (p<0.05). Infertility was more common in control group (65.5% vs. 10.8%; p<0.001). Fasting plasma glucose, basal FSH (follicle stimulating hormone) and estradiol (E2) levels were higher in study group than control group (p<0.05). Mean tumor marker levels were similar in both groups. Complete blood count values, smoking status, presence of PCOS, and number and size of polyps did not differ
significantly between the two groups. The most common location of endometrial polyps within the uterine cavity was the posterior wall. There was no correlation between number and size of polyps and basal hormone levels (p>0.05).
CONCLUSION: According to this study, 40 years of age and older women with endometrial polyps were more obese and had higher basal FSH and E2 levels. Obesity and increased estrogen levels may be contributing risk factors for developing endometrial polyps in women over 40 years of age. |
| first_indexed | 2024-04-10T10:26:02Z |
| format | Article |
| id | doaj.art-e71150752a4b43eba3912b52f7881315 |
| institution | Directory Open Access Journal |
| issn | 1300-4751 |
| language | English |
| last_indexed | 2024-04-10T10:26:02Z |
| publishDate | 2016-05-01 |
| publisher | Medical Network |
| record_format | Article |
| series | Gynecology Obstetrics & Reproductive Medicine |
| spelling | doaj.art-e71150752a4b43eba3912b52f78813152023-02-15T16:21:23ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512016-05-01203102The Effect of Age on Clinical and Laboratory Parameters in Reproductive Age Women with Endometrial PolypsAytekin Tokmak0Ebru Ersoy1Ali Özgür Ersoy2Esra Yaşar Çelik3Ali İrfan Güzel4Mustafa Uğur5Department of Obstetrics and Gynecology Dr. Zekai Tahir Burak Women’s Health Education and Research Hospital, AnkaraDepartment of Obstetrics and Gynecology Dr. Zekai Tahir Burak Women’s Health Education and Research Hospital, AnkaraDepartment of Obstetrics and Gynecology Dr. Zekai Tahir Burak Women’s Health Education and Research Hospital, AnkaraDepartment of Obstetrics and Gynecology Dr. Zekai Tahir Burak Women’s Health Education and Research Hospital, AnkaraDepartment of Obstetrics and Gynecology Dr. Zekai Tahir Burak Women’s Health Education and Research Hospital, AnkaraDepartment of Obstetrics and Gynecology Dr. Zekai Tahir Burak Women’s Health Education and Research Hospital, AnkaraOBJECTIVE: To compare clinical and laboratory parameters in middle and advanced reproductive age women with endometrial polyps. STUDY DESIGN: We designed a retrospective study among reproductive age women who were managed at our clinic with the diagnosis of endometrial polyps. Thirty seven women older than 40 years of age (study group), and 113 women younger than 40 years (control group) were compared in terms of various clinical and laboratory parameters including age, body mass index (BMI), gravidity, parity, abortion, basal hormone levels, tumor markers, complete blood count values, smoking status, presence of polycystic ovary syndrome (PCOS), infertility status, co-morbidities, and number and size of endometrial polyps. RESULTS: The mean age of patients in the study and control groups were 45.2±3.5 and 30.6±4.9 years, respectively (p<0.001). The median BMI, gravidity, parity and abortion were significantly higher in study group (p<0.05). Infertility was more common in control group (65.5% vs. 10.8%; p<0.001). Fasting plasma glucose, basal FSH (follicle stimulating hormone) and estradiol (E2) levels were higher in study group than control group (p<0.05). Mean tumor marker levels were similar in both groups. Complete blood count values, smoking status, presence of PCOS, and number and size of polyps did not differ significantly between the two groups. The most common location of endometrial polyps within the uterine cavity was the posterior wall. There was no correlation between number and size of polyps and basal hormone levels (p>0.05). CONCLUSION: According to this study, 40 years of age and older women with endometrial polyps were more obese and had higher basal FSH and E2 levels. Obesity and increased estrogen levels may be contributing risk factors for developing endometrial polyps in women over 40 years of age.http://gorm.com.tr/index.php/GORM/article/view/163Endometrial polyp, Reproductive age, Risk factors |
| spellingShingle | Aytekin Tokmak Ebru Ersoy Ali Özgür Ersoy Esra Yaşar Çelik Ali İrfan Güzel Mustafa Uğur The Effect of Age on Clinical and Laboratory Parameters in Reproductive Age Women with Endometrial Polyps Gynecology Obstetrics & Reproductive Medicine Endometrial polyp, Reproductive age, Risk factors |
| title | The Effect of Age on Clinical and Laboratory Parameters in Reproductive Age Women with Endometrial Polyps |
| title_full | The Effect of Age on Clinical and Laboratory Parameters in Reproductive Age Women with Endometrial Polyps |
| title_fullStr | The Effect of Age on Clinical and Laboratory Parameters in Reproductive Age Women with Endometrial Polyps |
| title_full_unstemmed | The Effect of Age on Clinical and Laboratory Parameters in Reproductive Age Women with Endometrial Polyps |
| title_short | The Effect of Age on Clinical and Laboratory Parameters in Reproductive Age Women with Endometrial Polyps |
| title_sort | effect of age on clinical and laboratory parameters in reproductive age women with endometrial polyps |
| topic | Endometrial polyp, Reproductive age, Risk factors |
| url | http://gorm.com.tr/index.php/GORM/article/view/163 |
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