| Summary: | Xiaoyan Hao, Honghai He, Liyuan Tao, Hongli Wang, Lili Zhao, Yi Ren, Peng Wang Medical Examination Center, Peking University, Third Hospital, Beijing, People’s Republic of ChinaCorrespondence: Peng Wang, Medical Examination Center, Peking University, Third Hospital, North Garden Road & 49, Beijing, People’s Republic of China, Tel +86-10-82266969, Fax +86-21-82265999, Email bysytjzx2022@163.comPurpose: This study investigated blood pressure and ventilation efficiency by cardiopulmonary exercise test (CPX) in different types of obesity aged 40– 60 years.Material and Methods: The inclusion criteria of this cross-sectional study were adults aged 40– 60 years underwent health checks. CPX was measured according to the relevant standards. According to different body mass index (BMI), there were 3 groups, BMI< 24 (kg/m2), 24≤BMI< 28 (kg/m2) and BMI≥ 28 (kg/m2). There were two groups in male, waist circumference≥ 90 (cm) and waist circumference< 90 (cm). Similarly, there were two groups in female, waist circumference≥ 85 (cm) and waist circumference< 85 (cm).Results: There were 543 individuals (64.6% male and 35.4% female) aged 40– 60 years in this study. The resting blood pressure (BP) and peak BP have the significant differences in different BMI groups (p < 0.001) and male or female groups (p < 0.001). However, the resting DBP (77.70± 9.45 vs 81.16± 8.80, p < 0.001) and peak DBP (85.67± 10.21 vs 89.03± 9.94, p = 0.002) have the significant differences in different male waist circumference groups, and the resting BP (SBP 113.76± 14.29 vs 121.86± 15.54, p = 0.001, DBP 71.95± 10.83 vs 77.27± 11.42, p = 0.005) has the significant differences in different female waist circumference groups. Carbon dioxide Ventilation equivalent (VE/VCO2) has the significant differences in different male waist circumference groups (26.84± 3.10 vs 27.68± 2.93, p = 0.009), but it has not the significant differences in different BMI groups and different female waist circumference groups. The oxygen pulse (VO2/HR) is slightly higher in female group than male group (0.93± 0.15 vs 0.89± 0.15, p = 0.001). Breathing reserve has the statistical significance in BMI ≥ 28 group compared with the BMI < 24 group (0.52± 0.13 vs 0.46± 0.17, ηp2=0.021).Conclusion: We found that the blood pressure and ventilation efficiency of CPX were different between the obesity and normal. This will provide a basis for accurate cardiopulmonary assessment of obesity.Keywords: resting blood pressure, peak blood pressure, carbon dioxide ventilation equivalent, central obesity
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