Intraoperative optical coherence tomography-assisted retrocorneal fibrous membrane biopsy and excision

Purpose: We report a case of retrocorneal fibrous membrane (RCFM) formation following penetrating keratoplasty (PK) and intraoperative optical coherence tomography (OCT)-guided excision of this membrane. Observations: A 68-year-old woman with primary open angle glaucoma and corneal decompensation of...

Full description

Bibliographic Details
Main Authors: Kelly Ruland, Thomas W. Bouldin, Richard M. Davis, David Fleischman
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:American Journal of Ophthalmology Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2451993618301117
_version_ 1818343882271752192
author Kelly Ruland
Thomas W. Bouldin
Richard M. Davis
David Fleischman
author_facet Kelly Ruland
Thomas W. Bouldin
Richard M. Davis
David Fleischman
author_sort Kelly Ruland
collection DOAJ
description Purpose: We report a case of retrocorneal fibrous membrane (RCFM) formation following penetrating keratoplasty (PK) and intraoperative optical coherence tomography (OCT)-guided excision of this membrane. Observations: A 68-year-old woman with primary open angle glaucoma and corneal decompensation of the right eye secondary to tube shunt presented for 3-month follow-up of PK. On examination of the right eye, the patient was noted to have a glassy pupillary membrane with traction on the iris. Anterior segment OCT confirmed a membrane connecting the iris to host cornea. The patient underwent biopsy and excision of the membrane assisted by intraoperative OCT. Pathological examination was consistent with Descemet's membrane proliferation. We suspect that this membrane represents retained host's Descemet's membrane following corneal transplantation. Conclusions: This case highlights the existence of RCFM formation in the context of retained host cornea following PK and the role of intraoperative OCT in management. Keywords: Retrocorneal fibrous membrane, Intraoperative optical coherence tomography, Descemet's membrane, Penetrating keratoplasty
first_indexed 2024-12-13T16:37:38Z
format Article
id doaj.art-e716c83857074241b1dd67556f8bea13
institution Directory Open Access Journal
issn 2451-9936
language English
last_indexed 2024-12-13T16:37:38Z
publishDate 2018-09-01
publisher Elsevier
record_format Article
series American Journal of Ophthalmology Case Reports
spelling doaj.art-e716c83857074241b1dd67556f8bea132022-12-21T23:38:22ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362018-09-0111101104Intraoperative optical coherence tomography-assisted retrocorneal fibrous membrane biopsy and excisionKelly Ruland0Thomas W. Bouldin1Richard M. Davis2David Fleischman3Drexel University College of Medicine, 2900 West Queen Lane, Philadelphia, PA, 19129, USADepartment of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, CB# 7525, Brinkhous-Bullitt Bldg, Chapel Hill, NC, 27599–7525, USADepartment of Ophthalmology, University of North Carolina at Chapel Hill, Kittner Eye Center, 2226 Nelson Highway, Chapel Hill, NC 27517, USADepartment of Ophthalmology, University of North Carolina at Chapel Hill, Kittner Eye Center, 2226 Nelson Highway, Chapel Hill, NC 27517, USA; Corresponding author. Department of Ophthalmology, University of North Carolina at Chapel Hill, 5126 Bioinformatics Bldg #7040, Chapel Hill, NC, 27599-7040, USA.Purpose: We report a case of retrocorneal fibrous membrane (RCFM) formation following penetrating keratoplasty (PK) and intraoperative optical coherence tomography (OCT)-guided excision of this membrane. Observations: A 68-year-old woman with primary open angle glaucoma and corneal decompensation of the right eye secondary to tube shunt presented for 3-month follow-up of PK. On examination of the right eye, the patient was noted to have a glassy pupillary membrane with traction on the iris. Anterior segment OCT confirmed a membrane connecting the iris to host cornea. The patient underwent biopsy and excision of the membrane assisted by intraoperative OCT. Pathological examination was consistent with Descemet's membrane proliferation. We suspect that this membrane represents retained host's Descemet's membrane following corneal transplantation. Conclusions: This case highlights the existence of RCFM formation in the context of retained host cornea following PK and the role of intraoperative OCT in management. Keywords: Retrocorneal fibrous membrane, Intraoperative optical coherence tomography, Descemet's membrane, Penetrating keratoplastyhttp://www.sciencedirect.com/science/article/pii/S2451993618301117
spellingShingle Kelly Ruland
Thomas W. Bouldin
Richard M. Davis
David Fleischman
Intraoperative optical coherence tomography-assisted retrocorneal fibrous membrane biopsy and excision
American Journal of Ophthalmology Case Reports
title Intraoperative optical coherence tomography-assisted retrocorneal fibrous membrane biopsy and excision
title_full Intraoperative optical coherence tomography-assisted retrocorneal fibrous membrane biopsy and excision
title_fullStr Intraoperative optical coherence tomography-assisted retrocorneal fibrous membrane biopsy and excision
title_full_unstemmed Intraoperative optical coherence tomography-assisted retrocorneal fibrous membrane biopsy and excision
title_short Intraoperative optical coherence tomography-assisted retrocorneal fibrous membrane biopsy and excision
title_sort intraoperative optical coherence tomography assisted retrocorneal fibrous membrane biopsy and excision
url http://www.sciencedirect.com/science/article/pii/S2451993618301117
work_keys_str_mv AT kellyruland intraoperativeopticalcoherencetomographyassistedretrocornealfibrousmembranebiopsyandexcision
AT thomaswbouldin intraoperativeopticalcoherencetomographyassistedretrocornealfibrousmembranebiopsyandexcision
AT richardmdavis intraoperativeopticalcoherencetomographyassistedretrocornealfibrousmembranebiopsyandexcision
AT davidfleischman intraoperativeopticalcoherencetomographyassistedretrocornealfibrousmembranebiopsyandexcision