Dietary polyphenols drive dose-dependent behavioral and molecular alterations to repeated morphine

Dietary polyphenols drive dose-dependent behavioral and molecular alterations to repeated morphine

Abstract Opioid Use Disorder (OUD) is associated with tremendous morbidity and mortality. Despite this burden, current pharmacotherapies for OUD are ineffective or intolerable for many patients. As such, interventions aimed at promoting resilience against OUD are of immense clinical interest. Treatm...

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Bibliographic Details
Main Authors: Aya Osman, Rebecca S. Hofford, Katherine R. Meckel, Yesha A. Dave, Sharon M. Zeldin, Ava L. Shipman, Kelsey E. Lucerne, Kyle J. Trageser, Tatsunori Oguchi, Drew D. Kiraly
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-39334-9

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