Predictive Efficacy of MiR-125b-5p, MiR-17-5p, and MiR-185-5p in Liver Metastasis and Chemotherapy Response Among Advanced Stage Colorectal Cancer Patients

Predictive Efficacy of MiR-125b-5p, MiR-17-5p, and MiR-185-5p in Liver Metastasis and Chemotherapy Response Among Advanced Stage Colorectal Cancer Patients

MicroRNAs (miRNAs), a class of small non-coding RNAs represent potential biomarkers for colorectal cancer (CRC). The study hypothesized that miRNAs associated with liver metastases may also contribute to assessing treatment response when associated to plasma exosomes. In this study, we used two sets...

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Bibliographic Details
Main Authors: Daniel Sur, Loredana Balacescu, Simona S. Cainap, Simona Visan, Laura Pop, Claudia Burz, Andrei Havasi, Rares Buiga, Calin Cainap, Alexandru Irimie, Ovidiu Balacescu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
biomarkers
exosomes
colorectal cancer
liver metastases
miR-125b-5p
miR-17-5p
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.651380/full

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