Radotinib enhances cytarabine (Ara-C)-induced acute myeloid leukemia cell death
Abstract Background Acute myeloid leukemia (AML) is a heterogeneous disease that frequently relapses after standard chemotherapy. Therefore, there is a need for the development of novel chemotherapeutic agents that could treat AML effectively. Radotinib, an oral BCR-ABL tyrosine kinase inhibitor, wa...
Main Authors: | Sook-Kyoung Heo, Eui-Kyu Noh, Ho-Min Yu, Do Kyoung Kim, Hye Jin Seo, Yoo Jin Lee, Jaekyung Cheon, Su Jin Koh, Young Joo Min, Yunsuk Choi, Jae-Cheol Jo |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2020-12-01
|
Series: | BMC Cancer |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12885-020-07701-8 |
Similar Items
-
Radotinib Decreases Prion Propagation and Prolongs Survival Times in Models of Prion Disease
by: Yeong-Gon Choi, et al.
Published: (2023-07-01) -
Determination of a radotinib dosage regimen based on dose–response relationships for the treatment of newly diagnosed patients with chronic myeloid leukemia
by: Hayeon Noh, et al.
Published: (2018-05-01) -
Diffuse purpuric eruption in a patient with acute myeloid leukemia
by: Zoha K. Momin, BS, et al.
Published: (2023-11-01) -
Concanavalin A staining: a potential biomarker to predict cytarabine sensitivity in acute myeloid leukemia
by: Tao Zhang, et al.
Published: (2024-01-01) -
Radotinib attenuates TGFβ -mediated pulmonary fibrosis in vitro and in vivo: exploring the potential of drug repurposing
by: Suji Baek, et al.
Published: (2022-12-01)