Angiogenesis mechanisms in transplantation of tissue-engineered constructions
There is a number of problems regarding bioengineered structures creation that require further study in the fi eld of regenerative medicine. One of the critical tasks that require solution is the fact that tissue engineered constructions, as a rule, are large, which signifi cantly limits the possibili...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | Russian |
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Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
2018-01-01
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Series: | Vestnik Transplantologii i Iskusstvennyh Organov |
Subjects: | |
Online Access: | https://journal.transpl.ru/vtio/article/view/838 |
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author | R. Z. Nakokhov E. A. Gubareva E. V. Kuevda A. S. Sotnichenko I. S. Gumenyuk G. M. Mogilnaya A. H. Kade |
author_facet | R. Z. Nakokhov E. A. Gubareva E. V. Kuevda A. S. Sotnichenko I. S. Gumenyuk G. M. Mogilnaya A. H. Kade |
author_sort | R. Z. Nakokhov |
collection | DOAJ |
description | There is a number of problems regarding bioengineered structures creation that require further study in the fi eld of regenerative medicine. One of the critical tasks that require solution is the fact that tissue engineered constructions, as a rule, are large, which signifi cantly limits the possibility of diffusion of nutrients and oxygen in them. Thus, the key task of fundamental medicine is to fi nd a technology for restoring the perfusion of the structures created. The article presents a modern overview of the mechanisms of angiogenesis and possible ways of its stimulation during transplantation of tissue engineered constructions. |
first_indexed | 2024-04-10T00:52:28Z |
format | Article |
id | doaj.art-e7242870316c4cbe945f53ed74a936ae |
institution | Directory Open Access Journal |
issn | 1995-1191 |
language | Russian |
last_indexed | 2024-04-10T00:52:28Z |
publishDate | 2018-01-01 |
publisher | Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov |
record_format | Article |
series | Vestnik Transplantologii i Iskusstvennyh Organov |
spelling | doaj.art-e7242870316c4cbe945f53ed74a936ae2023-03-13T10:37:24ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovVestnik Transplantologii i Iskusstvennyh Organov1995-11912018-01-0119414114510.15825/1995-1191-2017-4-141-145671Angiogenesis mechanisms in transplantation of tissue-engineered constructionsR. Z. Nakokhov0E. A. Gubareva1E. V. Kuevda2A. S. Sotnichenko3I. S. Gumenyuk4G. M. Mogilnaya5A. H. Kade6FSBEI HE «Kuban State Medical University».FSBEI HE «Kuban State Medical University».FSBEI HE «Kuban State Medical University».FSBEI HE «Kuban State Medical University».FSBEI HE «Kuban State Medical University».FSBEI HE «Kuban State Medical University».FSBEI HE «Kuban State Medical University».There is a number of problems regarding bioengineered structures creation that require further study in the fi eld of regenerative medicine. One of the critical tasks that require solution is the fact that tissue engineered constructions, as a rule, are large, which signifi cantly limits the possibility of diffusion of nutrients and oxygen in them. Thus, the key task of fundamental medicine is to fi nd a technology for restoring the perfusion of the structures created. The article presents a modern overview of the mechanisms of angiogenesis and possible ways of its stimulation during transplantation of tissue engineered constructions.https://journal.transpl.ru/vtio/article/view/838tissue engineeringangiogenesisgrowth factorsthree-dimensional matricesmultipotent mesenchymal stromal cells |
spellingShingle | R. Z. Nakokhov E. A. Gubareva E. V. Kuevda A. S. Sotnichenko I. S. Gumenyuk G. M. Mogilnaya A. H. Kade Angiogenesis mechanisms in transplantation of tissue-engineered constructions Vestnik Transplantologii i Iskusstvennyh Organov tissue engineering angiogenesis growth factors three-dimensional matrices multipotent mesenchymal stromal cells |
title | Angiogenesis mechanisms in transplantation of tissue-engineered constructions |
title_full | Angiogenesis mechanisms in transplantation of tissue-engineered constructions |
title_fullStr | Angiogenesis mechanisms in transplantation of tissue-engineered constructions |
title_full_unstemmed | Angiogenesis mechanisms in transplantation of tissue-engineered constructions |
title_short | Angiogenesis mechanisms in transplantation of tissue-engineered constructions |
title_sort | angiogenesis mechanisms in transplantation of tissue engineered constructions |
topic | tissue engineering angiogenesis growth factors three-dimensional matrices multipotent mesenchymal stromal cells |
url | https://journal.transpl.ru/vtio/article/view/838 |
work_keys_str_mv | AT rznakokhov angiogenesismechanismsintransplantationoftissueengineeredconstructions AT eagubareva angiogenesismechanismsintransplantationoftissueengineeredconstructions AT evkuevda angiogenesismechanismsintransplantationoftissueengineeredconstructions AT assotnichenko angiogenesismechanismsintransplantationoftissueengineeredconstructions AT isgumenyuk angiogenesismechanismsintransplantationoftissueengineeredconstructions AT gmmogilnaya angiogenesismechanismsintransplantationoftissueengineeredconstructions AT ahkade angiogenesismechanismsintransplantationoftissueengineeredconstructions |