| Summary: | The red lionfish (Pteroirs volitans) belongs to the family Scorpaenidae (scorpion fish). It is native to coral reefs in the Indian Ocean and western Pacific Ocean. Its poison consists of toxins that are water-soluble thermolabile polypeptides. The case of a 78-year-old white male is reported. He was a fisherman with a history of good health, normal body weight, who was conducting his normal fishing activities and was attacked by the lionfish. A necrotic tissue debridement was performed at the level of the left lower limb to the upper third. Surgery was decided, with a diagnosis of Fournier's gangrene, and a necrectomy was performed in a wide area. During his hospital stay, he underwent antibiotic treatment with crystalline penicillin, amikacin, metronidazole, meropenem, cefepime, sulfaprim, piperacillin. He was discharged alive on April 2, 2012.
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