Macrophage-specific responses to human- and animal-adapted tubercle bacilli reveal pathogen and host factors driving multinucleated cell formation.

Macrophage-specific responses to human- and animal-adapted tubercle bacilli reveal pathogen and host factors driving multinucleated cell formation.

The Mycobacterium tuberculosis complex (MTBC) is a group of related pathogens that cause tuberculosis (TB) in mammals. MTBC species are distinguished by their ability to sustain in distinct host populations. While Mycobacterium bovis (Mbv) sustains transmission cycles in cattle and wild animals and...

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Bibliografski detalji
Glavni autori: Christophe J Queval, Antony Fearns, Laure Botella, Alicia Smyth, Laura Schnettger, Morgane Mitermite, Esen Wooff, Bernardo Villarreal-Ramos, Waldo Garcia-Jimenez, Tiaan Heunis, Matthias Trost, Dirk Werling, Francisco J Salguero, Stephen V Gordon, Maximiliano G Gutierrez
Format: Članak
Jezik:English
Izdano: Public Library of Science (PLoS) 2021-03-01
Serija:PLoS Pathogens
Online pristup:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009410&type=printable

Internet

https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009410&type=printable

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