Core lipid, surface lipid and apolipoprotein composition analysis of lipoprotein particles as a function of particle size in one workflow integrating asymmetric flow field-flow fractionation and liquid chromatography-tandem mass spectrometry.

Core lipid, surface lipid and apolipoprotein composition analysis of lipoprotein particles as a function of particle size in one workflow integrating asymmetric flow field-flow fractionation and liquid chromatography-tandem mass spectrometry.

Lipoproteins are complex molecular assemblies that are key participants in the intricate cascade of extracellular lipid metabolism with important consequences in the formation of atherosclerotic lesions and the development of cardiovascular disease. Multiplexed mass spectrometry (MS) techniques have...

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Bibliographic Details
Main Authors: Zsuzsanna Kuklenyik, Jeffery I Jones, Michael S Gardner, David M Schieltz, Bryan A Parks, Christopher A Toth, Jon C Rees, Michael L Andrews, Kayla Carter, Antony K Lehtikoski, Lisa G McWilliams, Yulanda M Williamson, Kevin P Bierbaum, James L Pirkle, John R Barr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5892890?pdf=render

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