Urokinase System in Pathogenesis of Pulmonary Fibrosis: A Hidden Threat of COVID-19

Urokinase System in Pathogenesis of Pulmonary Fibrosis: A Hidden Threat of COVID-19

Pulmonary fibrosis is a common and threatening post-COVID-19 complication with poorly resolved molecular mechanisms and no established treatment. The plasminogen activator system, including urokinase (uPA) and urokinase receptor (uPAR), is involved in the pathogenesis of COVID-19 and contributes to...

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Bibliographic Details
Main Authors: Anna A. Shmakova, Vladimir S. Popov, Iliya P. Romanov, Nikita R. Khabibullin, Nailya R. Sabitova, Anna A. Karpukhina, Yana A. Kozhevnikova, Ella V. Kurilina, Zoya I. Tsokolaeva, Polina S. Klimovich, Kseniya A. Rubina, Yegor S. Vassetzky, Ekaterina V. Semina
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
COVID-19
pulmonary fibrosis
urokinase uPA
urokinase receptor uPAR
plasminogen
scRNA-seq
Online Access:https://www.mdpi.com/1422-0067/24/2/1382

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