Case Report: Recurrent retinal vein occlusion as the first clinical manifestation of systemic lupus erythematosus in a male patient [version 4; peer review: 2 approved]
Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease characterized by widespread clinical manifestations and immunological disorders. A myriad of ocular manifestations can be seen in patients with SLE. The most vision-threatening complication is vaso-occlusive retinopathy including re...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2022-06-01
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| Online Access: | https://f1000research.com/articles/10-761/v4 |
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| author | Olfa Berriche Jihen Chelly Wafa Ammari Sonia Hammami Fatma Arbi Marwa Ben Brahim Sondes Arfa Fadia Boubaker |
| author_facet | Olfa Berriche Jihen Chelly Wafa Ammari Sonia Hammami Fatma Arbi Marwa Ben Brahim Sondes Arfa Fadia Boubaker |
| author_sort | Olfa Berriche |
| collection | DOAJ |
| description | Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease characterized by widespread clinical manifestations and immunological disorders. A myriad of ocular manifestations can be seen in patients with SLE. The most vision-threatening complication is vaso-occlusive retinopathy including retinal vein occlusion (RVO). RVO associated with SLE is well described in the literature and its association with antiphospholipid antibodies is recognized. However, RVO as the initial manifestation of SLE is scarcely reported. Herein, we report the first case of recurrent RVO as the revealing manifestation of SLE in a 40-year-old male patient. He had two consecutive episodes of decreased vision. Ophthalmologic examination disclosed a branch retinal vein occlusion the first time and a central retinal vein occlusion the second time. The diagnosis of SLE was established based on clinical and immunological criteria. He was prescribed antiplatelet therapy, hydroxychloroquine at 5.5 mg/kg/day, and intravitreal anti-vascular endothelial growth factor (VEGF) antibodies regimen. He slowly improved under treatment. |
| first_indexed | 2024-04-13T09:37:06Z |
| format | Article |
| id | doaj.art-e72e2a01ba1043e3a7dd28b19acac075 |
| institution | Directory Open Access Journal |
| issn | 2046-1402 |
| language | English |
| last_indexed | 2024-04-13T09:37:06Z |
| publishDate | 2022-06-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | F1000Research |
| spelling | doaj.art-e72e2a01ba1043e3a7dd28b19acac0752022-12-22T02:52:04ZengF1000 Research LtdF1000Research2046-14022022-06-0110135108Case Report: Recurrent retinal vein occlusion as the first clinical manifestation of systemic lupus erythematosus in a male patient [version 4; peer review: 2 approved]Olfa Berriche0Jihen Chelly1Wafa Ammari2Sonia Hammami3Fatma Arbi4Marwa Ben Brahim5https://orcid.org/0000-0003-1967-0824Sondes Arfa6https://orcid.org/0000-0001-7797-4899Fadia Boubaker7Department of Internal Medicine and Endocrinology, Taher Sfar University Hospital, University of Monastir, Mahdia, 5100, TunisiaDepartment of Internal Medicine and Endocrinology, Taher Sfar University Hospital, University of Monastir, Mahdia, 5100, TunisiaDepartment of Ophthalmology, Taher Sfar University Hospital, University of Monastir, Mahdia, 5100, TunisiaDepartment of Internal Medicine and Endocrinology, Fattouma Bourguiba University Hospital, University of Monastir, Monastir, 5000, TunisiaDepartment of Internal Medicine and Endocrinology, Taher Sfar University Hospital, University of Monastir, Mahdia, 5100, TunisiaDepartment of Internal Medicine and Endocrinology, Taher Sfar University Hospital, University of Monastir, Mahdia, 5100, TunisiaDepartment of Internal Medicine and Endocrinology, Taher Sfar University Hospital, University of Monastir, Mahdia, 5100, TunisiaDepartment of Internal Medicine and Endocrinology, Taher Sfar University Hospital, University of Monastir, Mahdia, 5100, TunisiaSystemic lupus erythematosus (SLE) is a chronic, autoimmune disease characterized by widespread clinical manifestations and immunological disorders. A myriad of ocular manifestations can be seen in patients with SLE. The most vision-threatening complication is vaso-occlusive retinopathy including retinal vein occlusion (RVO). RVO associated with SLE is well described in the literature and its association with antiphospholipid antibodies is recognized. However, RVO as the initial manifestation of SLE is scarcely reported. Herein, we report the first case of recurrent RVO as the revealing manifestation of SLE in a 40-year-old male patient. He had two consecutive episodes of decreased vision. Ophthalmologic examination disclosed a branch retinal vein occlusion the first time and a central retinal vein occlusion the second time. The diagnosis of SLE was established based on clinical and immunological criteria. He was prescribed antiplatelet therapy, hydroxychloroquine at 5.5 mg/kg/day, and intravitreal anti-vascular endothelial growth factor (VEGF) antibodies regimen. He slowly improved under treatment.https://f1000research.com/articles/10-761/v4Retinal vein occlusion Systemic Lupus Erythematosus Male patient Intra-vitreal anti-vascular endothelial growth factor antibodies treatment case reporteng |
| spellingShingle | Olfa Berriche Jihen Chelly Wafa Ammari Sonia Hammami Fatma Arbi Marwa Ben Brahim Sondes Arfa Fadia Boubaker Case Report: Recurrent retinal vein occlusion as the first clinical manifestation of systemic lupus erythematosus in a male patient [version 4; peer review: 2 approved] F1000Research Retinal vein occlusion Systemic Lupus Erythematosus Male patient Intra-vitreal anti-vascular endothelial growth factor antibodies treatment case report eng |
| title | Case Report: Recurrent retinal vein occlusion as the first clinical manifestation of systemic lupus erythematosus in a male patient [version 4; peer review: 2 approved] |
| title_full | Case Report: Recurrent retinal vein occlusion as the first clinical manifestation of systemic lupus erythematosus in a male patient [version 4; peer review: 2 approved] |
| title_fullStr | Case Report: Recurrent retinal vein occlusion as the first clinical manifestation of systemic lupus erythematosus in a male patient [version 4; peer review: 2 approved] |
| title_full_unstemmed | Case Report: Recurrent retinal vein occlusion as the first clinical manifestation of systemic lupus erythematosus in a male patient [version 4; peer review: 2 approved] |
| title_short | Case Report: Recurrent retinal vein occlusion as the first clinical manifestation of systemic lupus erythematosus in a male patient [version 4; peer review: 2 approved] |
| title_sort | case report recurrent retinal vein occlusion as the first clinical manifestation of systemic lupus erythematosus in a male patient version 4 peer review 2 approved |
| topic | Retinal vein occlusion Systemic Lupus Erythematosus Male patient Intra-vitreal anti-vascular endothelial growth factor antibodies treatment case report eng |
| url | https://f1000research.com/articles/10-761/v4 |
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