The dynamics of morphological changes of facial skin in patients with malasseziasis at stages of antimycotic and anti-aging therapy

Background. Many questions about the dependence of pathological changes of the skin to age-appropriate background malassezia destruction require clarification and further advance, as well as the dependence of the effectiveness of anti-aging interventions of antimycotic therapy. Objective. The purpos...

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Main Author: Makarchuk A.O.
Format: Article
Language:Russian
Published: Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy 2015-03-01
Series:Морфологія
Subjects:
Online Access:http://www.morphology.dp.ua/_pub/MORPHO-2015-09-01/15maoaot.pdf
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author Makarchuk A.O.
author_facet Makarchuk A.O.
author_sort Makarchuk A.O.
collection DOAJ
description Background. Many questions about the dependence of pathological changes of the skin to age-appropriate background malassezia destruction require clarification and further advance, as well as the dependence of the effectiveness of anti-aging interventions of antimycotic therapy. Objective. The purpose of this study was to determine the morphological changes of the skin in patients with malasseziasis on stages of antimitotic and anti-aging therapy. Methods. In 90 patients with involutive changes in facial skin, including 60 patients with malasseziasis, using electron microscopy carried determine the state of the skin. Results. Found that specific antifungal therapy for 1 month prior to surgical intervention in the face provides the normalization of skin structures damaged by keratomicosis, through emulation of mitotic activity of keratinocytes in germinal zone and optimizing epidermal differentiation restricted vacuolization of epithelial cells. Prolongation of local and systemic antimycotic therapy within 1 month after the intervention was accompanied by reduction of involutive morphological changes of the skin and prevents development of malasseziasis recurrent for 1 year. Conclusion. Specific antimycotic therapy in patients with malasseziasis is essential for achieving high performance anti-aging activities. Citation: Makarchuk AO. [The dynamics of morphological changes of facial skin in patients with malasseziasis at stages of antimycotic and anti-aging therapy]. Morphologia. 2015;9(1):39-46. Ukrainian.
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spelling doaj.art-e72f2d8b307e4d49a92e106ab7db35d32022-12-22T01:36:01ZrusMinistry of Health of Ukraine. Dnipropetrovsk Medical AcademyМорфологія1997-96651997-96652015-03-01913946The dynamics of morphological changes of facial skin in patients with malasseziasis at stages of antimycotic and anti-aging therapyMakarchuk A.O.0Zaporizhzhia State Medical UniversityBackground. Many questions about the dependence of pathological changes of the skin to age-appropriate background malassezia destruction require clarification and further advance, as well as the dependence of the effectiveness of anti-aging interventions of antimycotic therapy. Objective. The purpose of this study was to determine the morphological changes of the skin in patients with malasseziasis on stages of antimitotic and anti-aging therapy. Methods. In 90 patients with involutive changes in facial skin, including 60 patients with malasseziasis, using electron microscopy carried determine the state of the skin. Results. Found that specific antifungal therapy for 1 month prior to surgical intervention in the face provides the normalization of skin structures damaged by keratomicosis, through emulation of mitotic activity of keratinocytes in germinal zone and optimizing epidermal differentiation restricted vacuolization of epithelial cells. Prolongation of local and systemic antimycotic therapy within 1 month after the intervention was accompanied by reduction of involutive morphological changes of the skin and prevents development of malasseziasis recurrent for 1 year. Conclusion. Specific antimycotic therapy in patients with malasseziasis is essential for achieving high performance anti-aging activities. Citation: Makarchuk AO. [The dynamics of morphological changes of facial skin in patients with malasseziasis at stages of antimycotic and anti-aging therapy]. Morphologia. 2015;9(1):39-46. Ukrainian.http://www.morphology.dp.ua/_pub/MORPHO-2015-09-01/15maoaot.pdfskininvolutive changesmalasseziasisultrastructure
spellingShingle Makarchuk A.O.
The dynamics of morphological changes of facial skin in patients with malasseziasis at stages of antimycotic and anti-aging therapy
Морфологія
skin
involutive changes
malasseziasis
ultrastructure
title The dynamics of morphological changes of facial skin in patients with malasseziasis at stages of antimycotic and anti-aging therapy
title_full The dynamics of morphological changes of facial skin in patients with malasseziasis at stages of antimycotic and anti-aging therapy
title_fullStr The dynamics of morphological changes of facial skin in patients with malasseziasis at stages of antimycotic and anti-aging therapy
title_full_unstemmed The dynamics of morphological changes of facial skin in patients with malasseziasis at stages of antimycotic and anti-aging therapy
title_short The dynamics of morphological changes of facial skin in patients with malasseziasis at stages of antimycotic and anti-aging therapy
title_sort dynamics of morphological changes of facial skin in patients with malasseziasis at stages of antimycotic and anti aging therapy
topic skin
involutive changes
malasseziasis
ultrastructure
url http://www.morphology.dp.ua/_pub/MORPHO-2015-09-01/15maoaot.pdf
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