A high-resolution map of transcriptional repression

A high-resolution map of transcriptional repression

Turning genes on and off is essential for development and homeostasis, yet little is known about the sequence and causal role of chromatin state changes during the repression of active genes. This is surprising, as defective gene silencing underlies developmental abnormalities and disease. Here we d...

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Bibliographic Details
Main Authors: Ziwei Liang, Karen E Brown, Thomas Carroll, Benjamin Taylor, Isabel Ferreirós Vidal, Brian Hendrich, David Rueda, Amanda G Fisher, Matthias Merkenschlager
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-03-01
Series:eLife
Subjects:
transcriptional repression
Ikaros
B cell
gene silencing
corepressor complex
Online Access:https://elifesciences.org/articles/22767

Internet

https://elifesciences.org/articles/22767

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