A Comparison of Magnetic Resonance Imaging Methods to Assess Multiple Sclerosis Lesions: Implications for Patient Characterization and Clinical Trial Design

A Comparison of Magnetic Resonance Imaging Methods to Assess Multiple Sclerosis Lesions: Implications for Patient Characterization and Clinical Trial Design

Magnetic resonance imaging (MRI) is a sensitive imaging modality for identifying inflammatory and/or demyelinating lesions, which is critical for a clinical diagnosis of MS and evaluating drug responses. There are many unique means of probing brain tissue status, including conventional T1 and T2 wei...

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Bibliographic Details
Main Authors: Ewart Mark Haacke, Evanthia Bernitsas, Karthik Subramanian, David Utriainen, Vinay Kumar Palutla, Kiran Yerramsetty, Prashanth Kumar, Sean K. Sethi, Yongsheng Chen, Zahid Latif, Pavan Jella, Sara Gharabaghi, Ying Wang, Xiaomeng Zhang, Robert A. Comley, John Beaver, Yanping Luo
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Diagnostics
Subjects:
multiple sclerosis
chronic white matter lesions
demyelinating/inflammatory lesions
quantitative magnetic resonance imaging
Online Access:https://www.mdpi.com/2075-4418/12/1/77

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