Pirin is a prognostic marker of human melanoma that dampens the proliferation of malignant cells by downregulating JARID1B/KDM5B expression

Pirin is a prognostic marker of human melanoma that dampens the proliferation of malignant cells by downregulating JARID1B/KDM5B expression

Abstract Originally considered to act as a transcriptional co-factor, Pirin has recently been reported to play a role in tumorigenesis and the malignant progression of many tumors. Here, we have analyzed the diagnostic and prognostic value of Pirin expression in the early stages of melanoma, and its...

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Bibliographic Details
Main Authors: Cristina Penas, Yoana Arroyo-Berdugo, Aintzane Apraiz, Javier Rasero, Iraia Muñoa-Hoyos, Noelia Andollo, Goikoane Cancho-Galán, Rosa Izu, Jesús Gardeazabal, Pilar A. Ezkurra, Nerea Subiran, Carmen Alvarez-Dominguez, Santos Alonso, Anja K. Bosserhoff, Aintzane Asumendi, María D. Boyano
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-36684-2

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https://doi.org/10.1038/s41598-023-36684-2

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