Evaluation of Homogentisic Acid, a Prospective Antibacterial Agent Highlighted by the Suitability of Nitisinone in Alkaptonuria 2 (SONIA 2) Clinical Trial

Evaluation of Homogentisic Acid, a Prospective Antibacterial Agent Highlighted by the Suitability of Nitisinone in Alkaptonuria 2 (SONIA 2) Clinical Trial

Despite urgent warnings about the spread of multidrug-resistant bacteria, the antibiotic development pipeline has remained sparsely populated. Naturally occurring antibacterial compounds may provide novel chemical starting points for antibiotic development programs and should be actively sought out....

Full description

Bibliographic Details
Main Authors: Nicola Ooi, Ian R. Cooper, Brendan Norman, James A. Gallagher, Nick Sireau, George Bou-Gharios, Lakshminarayan R. Ranganath, Victoria J. Savage
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cells
Subjects:
alkaptonuria
AKU
homogentisic acid
antimicrobial
bacteria
safety
Online Access:https://www.mdpi.com/2073-4409/12/13/1683

Similar Items

Similar Items