Liver toxicity from vitamin A

Hepatic toxicity secondary to hypervitaminosis A is extremely rare. We report the case of a 27‐year‐old Caucasian female who presented for an investigation of abdominal pain, cholestatic liver function tests, and abnormal computerized tomography findings. She had been prescribed isotretinoin for her...

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Main Authors: Rosanna Fox, Nigel Stace, Karen Wood, Claire French
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:JGH Open
Subjects:
Online Access:https://doi.org/10.1002/jgh3.12201
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author Rosanna Fox
Nigel Stace
Karen Wood
Claire French
author_facet Rosanna Fox
Nigel Stace
Karen Wood
Claire French
author_sort Rosanna Fox
collection DOAJ
description Hepatic toxicity secondary to hypervitaminosis A is extremely rare. We report the case of a 27‐year‐old Caucasian female who presented for an investigation of abdominal pain, cholestatic liver function tests, and abnormal computerized tomography findings. She had been prescribed isotretinoin for her acne and had subsequently purchased vitamin A online, which she consumed daily for over 18 months.
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spelling doaj.art-e73875177ac54f97986aa8ea41c7eea12022-12-21T21:56:47ZengWileyJGH Open2397-90702020-04-014228728810.1002/jgh3.12201Liver toxicity from vitamin ARosanna Fox0Nigel Stace1Karen Wood2Claire French3Department of Gastroenterology & Hepatology Wellington Regional Hospital Wellington New ZealandDepartment of Gastroenterology & Hepatology Wellington Regional Hospital Wellington New ZealandDepartment of Gastroenterology & Hepatology Wellington Regional Hospital Wellington New ZealandDepartment of Gastroenterology & Hepatology Wellington Regional Hospital Wellington New ZealandHepatic toxicity secondary to hypervitaminosis A is extremely rare. We report the case of a 27‐year‐old Caucasian female who presented for an investigation of abdominal pain, cholestatic liver function tests, and abnormal computerized tomography findings. She had been prescribed isotretinoin for her acne and had subsequently purchased vitamin A online, which she consumed daily for over 18 months.https://doi.org/10.1002/jgh3.12201drug‐induced liver injuryhepatic inflammationhypervitaminosis A
spellingShingle Rosanna Fox
Nigel Stace
Karen Wood
Claire French
Liver toxicity from vitamin A
JGH Open
drug‐induced liver injury
hepatic inflammation
hypervitaminosis A
title Liver toxicity from vitamin A
title_full Liver toxicity from vitamin A
title_fullStr Liver toxicity from vitamin A
title_full_unstemmed Liver toxicity from vitamin A
title_short Liver toxicity from vitamin A
title_sort liver toxicity from vitamin a
topic drug‐induced liver injury
hepatic inflammation
hypervitaminosis A
url https://doi.org/10.1002/jgh3.12201
work_keys_str_mv AT rosannafox livertoxicityfromvitamina
AT nigelstace livertoxicityfromvitamina
AT karenwood livertoxicityfromvitamina
AT clairefrench livertoxicityfromvitamina