Regional and sub-regional differences in hippocampal GABAergic neuronal vulnerability in the TgCRND8 mouse model of Alzheimer’s disease

Regional and sub-regional differences in hippocampal GABAergic neuronal vulnerability in the TgCRND8 mouse model of Alzheimer’s disease

Hippocampal network activity is predominantly coordinated by -amino-butyric acid (GABA)ergic neurons. We have previously hypothesized that the altered excitability of hippocampal neurons in Alzheimer's disease (AD), which manifests as increased in vivo susceptibility to seizures in the TgCRND8...

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Bibliographic Details
Main Authors: Marilia Silva Albequerque, Ian eMahar, Maria Antonietta eDavoli, Jean-Guy eChabot, Naguib eMechawar, Rémi eQuirion, Slavica eKrantic
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Aging Neuroscience
Subjects:
Neuropeptide Y
Somatostatin
Alzheimer’s disease
parvalbumin
hippocampal sub-regions
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00030/full

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