Appropriate Mechanical Confinement Inhibits Multipolar Cell Division via Pole-Cortex Interaction

Multipolar spindles are very rare in normal tissues, but they are much more prevalent in many tumors, which might be induced by the mechanical confinements from overcrowding microenvironments in tumors. However, little is known about what the difference is between various forms of mechanical confine...

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Bibliographic Details
Main Authors: Longcan Cheng, Jingchen Li, Houbo Sun, Hongyuan Jiang
Format: Article
Language:English
Published: American Physical Society 2023-03-01
Series:Physical Review X
Online Access:http://doi.org/10.1103/PhysRevX.13.011036