Comparative Analysis of Vascular Mimicry in Head and Neck Squamous Cell Carcinoma: In Vitro and In Vivo Approaches

Comparative Analysis of Vascular Mimicry in Head and Neck Squamous Cell Carcinoma: In Vitro and In Vivo Approaches

Tissue vasculature provides the main conduit for metastasis in solid tumours including head and neck squamous cell carcinoma (HNSCC). Vascular mimicry (VM) is an endothelial cell (EC)-independent neovascularization pattern, whereby tumour cells generate a perfusable vessel-like meshwork. Yet, despit...

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Bibliographic Details
Main Authors: Roosa Hujanen, Rabeia Almahmoudi, Tuula Salo, Abdelhakim Salem
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
Subjects:
head and neck squamous cell carcinoma
vascular mimicry
Matrigel
Myogel
zebrafish
metastasis
Online Access:https://www.mdpi.com/2072-6694/13/19/4747

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