A Bivalent Human Adenovirus Type 5 Vaccine Expressing the Rabies Virus Glycoprotein and Canine Distemper Virus Hemagglutinin Protein Confers Protective Immunity in Mice and Foxes

The development of a safe and efficient multivalent vaccine has great prospects for application. Both rabies virus (RABV) and canine distemper virus (CDV) are highly infectious antigens, causing lethal diseases in domestic dogs and other carnivores worldwide. In this study, a replication-deficient h...

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Bibliografiset tiedot
Päätekijät: Lina Yan, Zhongxin Zhao, Xianghong Xue, Wenwen Zheng, Tong Xu, Lele Liu, Li Tian, Xianwei Wang, Hongbin He, Xuexing Zheng
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: Frontiers Media S.A. 2020-06-01
Sarja:Frontiers in Microbiology
Aiheet:
Linkit:https://www.frontiersin.org/article/10.3389/fmicb.2020.01070/full