Metabolic control in patients with type 1 diabetes mellitus at the onset of primary adrenal insufficiency

Primary adrenal insufficiency is a rare disorder but it is more common in patients with type 1 diabetes mellitus (T1DM) or autoimmune thyroid diseases than in the general population. T1DM may precede the development of adrenocortical insufficiency. Addison’s disease can influence the glycemic contro...

Full description

Bibliographic Details
Format: Article
Language:English
Published: Endocrinology Research Centre 2013-06-01
Series:Ожирение и метаболизм
Subjects:
Online Access:https://www.omet-endojournals.ru/jour/article/view/4823
_version_ 1797204704638271488
collection DOAJ
description Primary adrenal insufficiency is a rare disorder but it is more common in patients with type 1 diabetes mellitus (T1DM) or autoimmune thyroid diseases than in the general population. T1DM may precede the development of adrenocortical insufficiency. Addison’s disease can influence the glycemic control in patients with T1DM worsening glucose metabolism. It causes the decrease of gluconeogenesis, reduction in total insulin requirement and rather often «unexplained» recurrent hypoglycemia. Glucocorticoid replacement therapy in patients with primary adrenal insufficiency and T1DM increases the insulin requirement. The article presents the development of primary adrenal insufficiency in a patient with type 1 DM and autoimmune hypothyroidism, accompanied with incidents of recurrent hypoglycemia.
first_indexed 2024-03-08T09:14:41Z
format Article
id doaj.art-e7453551e3754e0ab6a6eea8fc5e25bf
institution Directory Open Access Journal
issn 2071-8713
2306-5524
language English
last_indexed 2024-04-24T08:39:28Z
publishDate 2013-06-01
publisher Endocrinology Research Centre
record_format Article
series Ожирение и метаболизм
spelling doaj.art-e7453551e3754e0ab6a6eea8fc5e25bf2024-04-16T16:16:08ZengEndocrinology Research CentreОжирение и метаболизм2071-87132306-55242013-06-01102384110.14341/2071-8713-48234781Metabolic control in patients with type 1 diabetes mellitus at the onset of primary adrenal insufficiencyPrimary adrenal insufficiency is a rare disorder but it is more common in patients with type 1 diabetes mellitus (T1DM) or autoimmune thyroid diseases than in the general population. T1DM may precede the development of adrenocortical insufficiency. Addison’s disease can influence the glycemic control in patients with T1DM worsening glucose metabolism. It causes the decrease of gluconeogenesis, reduction in total insulin requirement and rather often «unexplained» recurrent hypoglycemia. Glucocorticoid replacement therapy in patients with primary adrenal insufficiency and T1DM increases the insulin requirement. The article presents the development of primary adrenal insufficiency in a patient with type 1 DM and autoimmune hypothyroidism, accompanied with incidents of recurrent hypoglycemia.https://www.omet-endojournals.ru/jour/article/view/4823adrenal insufficiencytype 1 diabetes mellitusrecurrent hypoglycemiaaps type 2
spellingShingle Metabolic control in patients with type 1 diabetes mellitus at the onset of primary adrenal insufficiency
Ожирение и метаболизм
adrenal insufficiency
type 1 diabetes mellitus
recurrent hypoglycemia
aps type 2
title Metabolic control in patients with type 1 diabetes mellitus at the onset of primary adrenal insufficiency
title_full Metabolic control in patients with type 1 diabetes mellitus at the onset of primary adrenal insufficiency
title_fullStr Metabolic control in patients with type 1 diabetes mellitus at the onset of primary adrenal insufficiency
title_full_unstemmed Metabolic control in patients with type 1 diabetes mellitus at the onset of primary adrenal insufficiency
title_short Metabolic control in patients with type 1 diabetes mellitus at the onset of primary adrenal insufficiency
title_sort metabolic control in patients with type 1 diabetes mellitus at the onset of primary adrenal insufficiency
topic adrenal insufficiency
type 1 diabetes mellitus
recurrent hypoglycemia
aps type 2
url https://www.omet-endojournals.ru/jour/article/view/4823