Postnatal developmental dynamics of cell type specification genes in Brn3a/Pou4f1 Retinal Ganglion Cells

Postnatal developmental dynamics of cell type specification genes in Brn3a/Pou4f1 Retinal Ganglion Cells

Abstract Background About 20–30 distinct Retinal Ganglion Cell (RGC) types transmit visual information from the retina to the brain. The developmental mechanisms by which RGCs are specified are still largely unknown. Brn3a is a member of the Brn3/Pou4f transcription factor family, which contains key...

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Bibliographic Details
Main Authors: Vladimir Vladimirovich Muzyka, Matthew Brooks, Tudor Constantin Badea
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Neural Development
Subjects:
Retinal ganglion cell
Subtype specification
Postnatal development
Brn3a
RNA sequencing
in situ hybridization
Online Access:http://link.springer.com/article/10.1186/s13064-018-0110-0

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