Case report: Open bite as an extrapyramidal side effect with aripiprazole, a dopamine partial agonist

Long-term, fixed-point posttreatment observation of orthodontically treated patients provided us with the opportunity to capture the onset, development, and improvement of open bite, a type of malocclusion. Based on the chronological sequence of events, i.e., a tendency for open bite to worsen with...

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Main Authors: Satoko Sumi, Takahiko Nagamine, Koji Sumi, Reona Aijima, Kyoko Oka, Akira Toyofuku
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2022.976387/full
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author Satoko Sumi
Takahiko Nagamine
Takahiko Nagamine
Koji Sumi
Reona Aijima
Kyoko Oka
Akira Toyofuku
author_facet Satoko Sumi
Takahiko Nagamine
Takahiko Nagamine
Koji Sumi
Reona Aijima
Kyoko Oka
Akira Toyofuku
author_sort Satoko Sumi
collection DOAJ
description Long-term, fixed-point posttreatment observation of orthodontically treated patients provided us with the opportunity to capture the onset, development, and improvement of open bite, a type of malocclusion. Based on the chronological sequence of events, i.e., a tendency for open bite to worsen with increasing aripiprazole dosage and to improve with decreasing dosage, it was inferred that the onset of malocclusion was caused by extrapyramidal symptoms related to aripiprazole dosage. Physicians should be aware of this side effect when prescribing aripiprazole to children and adolescents. Careful consideration of medication history is necessary when dentists treat open bite in children and adolescents.
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spelling doaj.art-e747a933ea7f4e84a729866cb977caef2022-12-22T04:25:25ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402022-09-011310.3389/fpsyt.2022.976387976387Case report: Open bite as an extrapyramidal side effect with aripiprazole, a dopamine partial agonistSatoko Sumi0Takahiko Nagamine1Takahiko Nagamine2Koji Sumi3Reona Aijima4Kyoko Oka5Akira Toyofuku6Section of Pediatric Dentistry, Department of Oral Growth and Development, Fukuoka Dental College, Fukuoka, JapanSunlight Brain Research Center, Hofu, JapanDepartment of Psychosomatic Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, JapanSumi Orthodontic Clinic, Saga, JapanDepartment of Oral and Maxillofacial Surgery, Faculty of Medicine, Saga University, Saga, JapanSection of Pediatric Dentistry, Department of Oral Growth and Development, Fukuoka Dental College, Fukuoka, JapanDepartment of Psychosomatic Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, JapanLong-term, fixed-point posttreatment observation of orthodontically treated patients provided us with the opportunity to capture the onset, development, and improvement of open bite, a type of malocclusion. Based on the chronological sequence of events, i.e., a tendency for open bite to worsen with increasing aripiprazole dosage and to improve with decreasing dosage, it was inferred that the onset of malocclusion was caused by extrapyramidal symptoms related to aripiprazole dosage. Physicians should be aware of this side effect when prescribing aripiprazole to children and adolescents. Careful consideration of medication history is necessary when dentists treat open bite in children and adolescents.https://www.frontiersin.org/articles/10.3389/fpsyt.2022.976387/fullopen biteextrapyramidal side effectaripiprazoleorthodontic treatmentadolescent
spellingShingle Satoko Sumi
Takahiko Nagamine
Takahiko Nagamine
Koji Sumi
Reona Aijima
Kyoko Oka
Akira Toyofuku
Case report: Open bite as an extrapyramidal side effect with aripiprazole, a dopamine partial agonist
Frontiers in Psychiatry
open bite
extrapyramidal side effect
aripiprazole
orthodontic treatment
adolescent
title Case report: Open bite as an extrapyramidal side effect with aripiprazole, a dopamine partial agonist
title_full Case report: Open bite as an extrapyramidal side effect with aripiprazole, a dopamine partial agonist
title_fullStr Case report: Open bite as an extrapyramidal side effect with aripiprazole, a dopamine partial agonist
title_full_unstemmed Case report: Open bite as an extrapyramidal side effect with aripiprazole, a dopamine partial agonist
title_short Case report: Open bite as an extrapyramidal side effect with aripiprazole, a dopamine partial agonist
title_sort case report open bite as an extrapyramidal side effect with aripiprazole a dopamine partial agonist
topic open bite
extrapyramidal side effect
aripiprazole
orthodontic treatment
adolescent
url https://www.frontiersin.org/articles/10.3389/fpsyt.2022.976387/full
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