Grandi Byen—supporting child growth and development through integrated, responsive parenting, nutrition and hygiene: study protocol for a randomized controlled trial
Abstract Background Poor child growth and development outcomes stem from complex relationships encompassing biological, behavioral, social, and environmental conditions. However, there is a dearth of research on integrated approaches targeting these interwoven factors. The Grandi Byen study seeks to...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-01-01
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| Series: | BMC Pediatrics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12887-021-03089-x |
| _version_ | 1818954019735863296 |
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| author | Patricia L. Kohl Emmanuel A. Gyimah Jenna Diaz F. Matthew Kuhlmann Sherlie Jean-Louis Dulience Fithi Embaye Derek S. Brown Shenyang Guo Joan L. Luby Jennifer L. Nicholas Jay Turner Melissa Chapnick Joseline Marhone Pierre Jacques Boncy Rony St. Fleur Maureen M. Black Lora L. Iannotti |
| author_facet | Patricia L. Kohl Emmanuel A. Gyimah Jenna Diaz F. Matthew Kuhlmann Sherlie Jean-Louis Dulience Fithi Embaye Derek S. Brown Shenyang Guo Joan L. Luby Jennifer L. Nicholas Jay Turner Melissa Chapnick Joseline Marhone Pierre Jacques Boncy Rony St. Fleur Maureen M. Black Lora L. Iannotti |
| author_sort | Patricia L. Kohl |
| collection | DOAJ |
| description | Abstract Background Poor child growth and development outcomes stem from complex relationships encompassing biological, behavioral, social, and environmental conditions. However, there is a dearth of research on integrated approaches targeting these interwoven factors. The Grandi Byen study seeks to fill this research gap through a three-arm longitudinal randomized controlled trial which will evaluate the impact of an integrated nutrition, responsive parenting, and WASH (water, sanitation and hygiene) intervention on holistic child growth and development. Methods We will recruit 600 mother-infant dyads living in Cap-Haitien, Haiti and randomize them equally into one of the following groups: 1) standard well-baby care; 2) nutritional intervention (one egg per day for 6 months); and 3) multicomponent Grandi Byen intervention (responsive parenting, nutrition, WASH + one egg per day for 6 months). Primary outcomes include child growth as well as cognitive, language, motor, and social-emotional development. The study also assesses other indicators of child health (bone maturation, brain growth, diarrheal morbidity and allergies, dietary intake, nutrient biomarkers) along with responsive parenting as mediating factors influencing the primary outcomes. An economic evaluation will assess the feasibility of large-scale implementation of the interventions. Discussion This study builds on research highlighting the importance of responsive parenting interventions on overall child health, as well as evidence demonstrating that providing an egg daily to infants during the complementary feeding period can prevent stunted growth. The multicomponent Grandi Byen intervention may provide evidence of synergistic or mediating effects of an egg intervention with instruction on psychoeducational parenting and WASH on child growth and development. Grandi Byen presents key innovations with implications for the well-being of children living in poverty globally. Trial registration NCT04785352 . Registered March 5, 2021 at https://clinicaltrials.gov/ |
| first_indexed | 2024-12-20T10:15:31Z |
| format | Article |
| id | doaj.art-e74b52e649ed4a3daa7c1bb9c0f1cf95 |
| institution | Directory Open Access Journal |
| issn | 1471-2431 |
| language | English |
| last_indexed | 2024-12-20T10:15:31Z |
| publishDate | 2022-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pediatrics |
| spelling | doaj.art-e74b52e649ed4a3daa7c1bb9c0f1cf952022-12-21T19:44:04ZengBMCBMC Pediatrics1471-24312022-01-0122111810.1186/s12887-021-03089-xGrandi Byen—supporting child growth and development through integrated, responsive parenting, nutrition and hygiene: study protocol for a randomized controlled trialPatricia L. Kohl0Emmanuel A. Gyimah1Jenna Diaz2F. Matthew Kuhlmann3Sherlie Jean-Louis Dulience4Fithi Embaye5Derek S. Brown6Shenyang Guo7Joan L. Luby8Jennifer L. Nicholas9Jay Turner10Melissa Chapnick11Joseline Marhone Pierre12Jacques Boncy13Rony St. Fleur14Maureen M. Black15Lora L. Iannotti16Brown School, Washington University in St. LouisBrown School, Washington University in St. LouisDivision of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Washington University School of Medicine in St. LouisDivision of Infectious Diseases, Washington University School of Medicine in St. LouisBrown School, Washington University in St. LouisBrown School, Washington University in St. LouisBrown School, Washington University in St. LouisBrown School, Washington University in St. LouisDepartment of Psychiatry, Washington University School of Medicine in St. LouisDepartment of Radiology, School of Medicine, Case Western Reserve UniversityMcKelvey School of Engineering, Washington University in St. LouisBrown School, Washington University in St. LouisUnité de Coordination du Programme National d’Alimentation et de Nutrition, Ministère de la Santé Publique et de la PopulationLaboratoire National de Santé Publique, Ministère de la Santé Publique et de la PopulationHôpital Universitaire JustinienDepartment of Pediatrics, University of Maryland School of MedicineBrown School, Washington University in St. LouisAbstract Background Poor child growth and development outcomes stem from complex relationships encompassing biological, behavioral, social, and environmental conditions. However, there is a dearth of research on integrated approaches targeting these interwoven factors. The Grandi Byen study seeks to fill this research gap through a three-arm longitudinal randomized controlled trial which will evaluate the impact of an integrated nutrition, responsive parenting, and WASH (water, sanitation and hygiene) intervention on holistic child growth and development. Methods We will recruit 600 mother-infant dyads living in Cap-Haitien, Haiti and randomize them equally into one of the following groups: 1) standard well-baby care; 2) nutritional intervention (one egg per day for 6 months); and 3) multicomponent Grandi Byen intervention (responsive parenting, nutrition, WASH + one egg per day for 6 months). Primary outcomes include child growth as well as cognitive, language, motor, and social-emotional development. The study also assesses other indicators of child health (bone maturation, brain growth, diarrheal morbidity and allergies, dietary intake, nutrient biomarkers) along with responsive parenting as mediating factors influencing the primary outcomes. An economic evaluation will assess the feasibility of large-scale implementation of the interventions. Discussion This study builds on research highlighting the importance of responsive parenting interventions on overall child health, as well as evidence demonstrating that providing an egg daily to infants during the complementary feeding period can prevent stunted growth. The multicomponent Grandi Byen intervention may provide evidence of synergistic or mediating effects of an egg intervention with instruction on psychoeducational parenting and WASH on child growth and development. Grandi Byen presents key innovations with implications for the well-being of children living in poverty globally. Trial registration NCT04785352 . Registered March 5, 2021 at https://clinicaltrials.gov/https://doi.org/10.1186/s12887-021-03089-xStuntingResponsive parentingChild developmentIntegrated parenting interventionNutrition |
| spellingShingle | Patricia L. Kohl Emmanuel A. Gyimah Jenna Diaz F. Matthew Kuhlmann Sherlie Jean-Louis Dulience Fithi Embaye Derek S. Brown Shenyang Guo Joan L. Luby Jennifer L. Nicholas Jay Turner Melissa Chapnick Joseline Marhone Pierre Jacques Boncy Rony St. Fleur Maureen M. Black Lora L. Iannotti Grandi Byen—supporting child growth and development through integrated, responsive parenting, nutrition and hygiene: study protocol for a randomized controlled trial BMC Pediatrics Stunting Responsive parenting Child development Integrated parenting intervention Nutrition |
| title | Grandi Byen—supporting child growth and development through integrated, responsive parenting, nutrition and hygiene: study protocol for a randomized controlled trial |
| title_full | Grandi Byen—supporting child growth and development through integrated, responsive parenting, nutrition and hygiene: study protocol for a randomized controlled trial |
| title_fullStr | Grandi Byen—supporting child growth and development through integrated, responsive parenting, nutrition and hygiene: study protocol for a randomized controlled trial |
| title_full_unstemmed | Grandi Byen—supporting child growth and development through integrated, responsive parenting, nutrition and hygiene: study protocol for a randomized controlled trial |
| title_short | Grandi Byen—supporting child growth and development through integrated, responsive parenting, nutrition and hygiene: study protocol for a randomized controlled trial |
| title_sort | grandi byen supporting child growth and development through integrated responsive parenting nutrition and hygiene study protocol for a randomized controlled trial |
| topic | Stunting Responsive parenting Child development Integrated parenting intervention Nutrition |
| url | https://doi.org/10.1186/s12887-021-03089-x |
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