<i>IDH1</i> Targeting as a New Potential Option for Intrahepatic Cholangiocarcinoma Treatment—Current State and Future Perspectives

<i>IDH1</i> Targeting as a New Potential Option for Intrahepatic Cholangiocarcinoma Treatment—Current State and Future Perspectives

Cholangiocarcinoma is a primary malignancy of the biliary tract characterized by late and unspecific symptoms, unfavorable prognosis, and few treatment options. The advent of next-generation sequencing has revealed potential targetable or actionable molecular alterations in biliary tumors. Among sev...

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Bibliographic Details
Main Authors: Fabiana Crispo, Michele Pietrafesa, Valentina Condelli, Francesca Maddalena, Giuseppina Bruno, Annamaria Piscazzi, Alessandro Sgambato, Franca Esposito, Matteo Landriscina
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Molecules
Subjects:
intrahepatic cholangiocarcinoma
isocitrate dehydrogenase
2-hydroxyglutarate
<i>IDH1</i> inhibitors
Online Access:https://www.mdpi.com/1420-3049/25/16/3754

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