Function of Na/K-pump in Excitable Tissues (Review)
Na/K-ATPase is a key enzyme supporting asymmetric distribution of Na and K ions on the outer cell membrane of animal tissues. In the review, current state of Na-pump function is discussed. The data are presented describing molecular properties and location of the enzyme molecule within the cell memb...
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| Format: | Article |
| Language: | English |
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Siberian Federal University
2008-09-01
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| Series: | Журнал Сибирского федерального университета: Серия Биология |
| Subjects: | |
| Online Access: | http://elib.sfu-kras.ru/bitstream/2311/936/1/03_%d0%91%d0%be%d0%bb%d0%b4%d1%8b%d1%80%d0%b5%d0%b2.pdf |
| Summary: | Na/K-ATPase is a key enzyme supporting asymmetric distribution of Na and K ions on the outer cell membrane of animal tissues. In the review, current state of Na-pump function is discussed. The data are presented describing molecular properties and location of the enzyme molecule within the cell membrane. Evidence on oligomeric structure of Na/K-ATPase and regulation of the protomers within the complex by ATP are shown. New data illustrating participation of Na/K-pump in cell signaling are presented. |
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| ISSN: | 1997-1389 2313-5530 |