Function of Na/K-pump in Excitable Tissues (Review)
Na/K-ATPase is a key enzyme supporting asymmetric distribution of Na and K ions on the outer cell membrane of animal tissues. In the review, current state of Na-pump function is discussed. The data are presented describing molecular properties and location of the enzyme molecule within the cell memb...
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| Format: | Article |
| Language: | English |
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Siberian Federal University
2008-09-01
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| Series: | Журнал Сибирского федерального университета: Серия Биология |
| Subjects: | |
| Online Access: | http://elib.sfu-kras.ru/bitstream/2311/936/1/03_%d0%91%d0%be%d0%bb%d0%b4%d1%8b%d1%80%d0%b5%d0%b2.pdf |
| _version_ | 1819132637952868352 |
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| author | Alexander A. Boldyrev |
| author_facet | Alexander A. Boldyrev |
| author_sort | Alexander A. Boldyrev |
| collection | DOAJ |
| description | Na/K-ATPase is a key enzyme supporting asymmetric distribution of Na and K ions on the outer cell membrane of animal tissues. In the review, current state of Na-pump function is discussed. The data are presented describing molecular properties and location of the enzyme molecule within the cell membrane. Evidence on oligomeric structure of Na/K-ATPase and regulation of the protomers within the complex by ATP are shown. New data illustrating participation of Na/K-pump in cell signaling are presented. |
| first_indexed | 2024-12-22T09:34:34Z |
| format | Article |
| id | doaj.art-e75dc58ed5a44cb5a655513f2597fa05 |
| institution | Directory Open Access Journal |
| issn | 1997-1389 2313-5530 |
| language | English |
| last_indexed | 2024-12-22T09:34:34Z |
| publishDate | 2008-09-01 |
| publisher | Siberian Federal University |
| record_format | Article |
| series | Журнал Сибирского федерального университета: Серия Биология |
| spelling | doaj.art-e75dc58ed5a44cb5a655513f2597fa052022-12-21T18:30:52ZengSiberian Federal UniversityЖурнал Сибирского федерального университета: Серия Биология1997-13892313-55302008-09-0113206225http://elib.sfu-kras.ru/handle/2311/936Function of Na/K-pump in Excitable Tissues (Review)Alexander A. Boldyrev0International Biotechnological Center of Lomonosov Moscow State University, Vorobievy Gory, Moscow, 119991 RussiaNa/K-ATPase is a key enzyme supporting asymmetric distribution of Na and K ions on the outer cell membrane of animal tissues. In the review, current state of Na-pump function is discussed. The data are presented describing molecular properties and location of the enzyme molecule within the cell membrane. Evidence on oligomeric structure of Na/K-ATPase and regulation of the protomers within the complex by ATP are shown. New data illustrating participation of Na/K-pump in cell signaling are presented.http://elib.sfu-kras.ru/bitstream/2311/936/1/03_%d0%91%d0%be%d0%bb%d0%b4%d1%8b%d1%80%d0%b5%d0%b2.pdfna/k-atpaseoligomeric structureatpsodiumpotassiumcell signaling |
| spellingShingle | Alexander A. Boldyrev Function of Na/K-pump in Excitable Tissues (Review) Журнал Сибирского федерального университета: Серия Биология na/k-atpase oligomeric structure atp sodium potassium cell signaling |
| title | Function of Na/K-pump in Excitable Tissues (Review) |
| title_full | Function of Na/K-pump in Excitable Tissues (Review) |
| title_fullStr | Function of Na/K-pump in Excitable Tissues (Review) |
| title_full_unstemmed | Function of Na/K-pump in Excitable Tissues (Review) |
| title_short | Function of Na/K-pump in Excitable Tissues (Review) |
| title_sort | function of na k pump in excitable tissues review |
| topic | na/k-atpase oligomeric structure atp sodium potassium cell signaling |
| url | http://elib.sfu-kras.ru/bitstream/2311/936/1/03_%d0%91%d0%be%d0%bb%d0%b4%d1%8b%d1%80%d0%b5%d0%b2.pdf |
| work_keys_str_mv | AT alexanderaboldyrev functionofnakpumpinexcitabletissuesreview |