NLRP3 Inflammasome Is Involved in Cocaine-Mediated Potentiation on Behavioral Changes in CX3CR1-Deficient Mice

Microglia, the primary immunocompetent cells of the brain, are suggested to play a role in the development of drug addiction. Previous studies have identified the microglia-derived pro-inflammatory factor IL1β can promote the progression of cocaine addiction. Additionally, the activation status of m...

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Bibliographic Details
Main Authors: Ming-Lei Guo, Ernest T. Chivero, Shannon E. Callen, Shilpa Buch
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Journal of Personalized Medicine
Subjects:
Online Access:https://www.mdpi.com/2075-4426/11/10/963