Strategies of LncRNA DLX6-AS1 on Study and Therapeutics
Accumulating evidence has revealed the vital regulatory roles of lncRNA DLX6-AS1 in various tumors at pre-transcriptional, transcriptional, and post-transcriptional levels, which makes it a potential prognosis factor and therapeutic target. In addition, the presence of lncRNA DLX6-AS1 in the exosome...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-06-01
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| Series: | Frontiers in Genetics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fgene.2022.871988/full |
| _version_ | 1828724253340467200 |
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| author | Yanyan Zhao Pei Li |
| author_facet | Yanyan Zhao Pei Li |
| author_sort | Yanyan Zhao |
| collection | DOAJ |
| description | Accumulating evidence has revealed the vital regulatory roles of lncRNA DLX6-AS1 in various tumors at pre-transcriptional, transcriptional, and post-transcriptional levels, which makes it a potential prognosis factor and therapeutic target. In addition, the presence of lncRNA DLX6-AS1 in the exosomes of peripheral blood of patients with tumors may also contribute to it being a possible cancer-related biomarker. However, most literature studies are devoted to studying the effect of lncRNA DLX6-AS1 as a sponging molecule of miRNAs, the research of which is likely to get stuck into a dilemma. Literature studies published already have demonstrated an exciting cell malignant phenotype inhibition with the knockdown of lncRNA DLX6-AS1 in various tumor cell lines. With the comprehensive development of delivery systems, high-throughput sequencing, and aptamers, the problems of finding novel research methods and exploring the therapeutic options which are based on lncRNA DLX6-AS1 in vivo could come into a period to deal with. This review aims to summarize the research statuses of lncRNA DLX6-AS1, discuss other study methodologies and therapeutic strategies on it, which might be of help to the deep learning of lncRNA DLX6-AS1 and its application from basic to clinical research. |
| first_indexed | 2024-04-12T13:05:19Z |
| format | Article |
| id | doaj.art-e7621faa4a4f46d993659bc09d80c9d0 |
| institution | Directory Open Access Journal |
| issn | 1664-8021 |
| language | English |
| last_indexed | 2024-04-12T13:05:19Z |
| publishDate | 2022-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Genetics |
| spelling | doaj.art-e7621faa4a4f46d993659bc09d80c9d02022-12-22T03:32:04ZengFrontiers Media S.A.Frontiers in Genetics1664-80212022-06-011310.3389/fgene.2022.871988871988Strategies of LncRNA DLX6-AS1 on Study and TherapeuticsYanyan ZhaoPei LiAccumulating evidence has revealed the vital regulatory roles of lncRNA DLX6-AS1 in various tumors at pre-transcriptional, transcriptional, and post-transcriptional levels, which makes it a potential prognosis factor and therapeutic target. In addition, the presence of lncRNA DLX6-AS1 in the exosomes of peripheral blood of patients with tumors may also contribute to it being a possible cancer-related biomarker. However, most literature studies are devoted to studying the effect of lncRNA DLX6-AS1 as a sponging molecule of miRNAs, the research of which is likely to get stuck into a dilemma. Literature studies published already have demonstrated an exciting cell malignant phenotype inhibition with the knockdown of lncRNA DLX6-AS1 in various tumor cell lines. With the comprehensive development of delivery systems, high-throughput sequencing, and aptamers, the problems of finding novel research methods and exploring the therapeutic options which are based on lncRNA DLX6-AS1 in vivo could come into a period to deal with. This review aims to summarize the research statuses of lncRNA DLX6-AS1, discuss other study methodologies and therapeutic strategies on it, which might be of help to the deep learning of lncRNA DLX6-AS1 and its application from basic to clinical research.https://www.frontiersin.org/articles/10.3389/fgene.2022.871988/fulllncRNA DLX6-AS1regulatory mechanismtumornovel research methodologiestherapeutic strategies |
| spellingShingle | Yanyan Zhao Pei Li Strategies of LncRNA DLX6-AS1 on Study and Therapeutics Frontiers in Genetics lncRNA DLX6-AS1 regulatory mechanism tumor novel research methodologies therapeutic strategies |
| title | Strategies of LncRNA DLX6-AS1 on Study and Therapeutics |
| title_full | Strategies of LncRNA DLX6-AS1 on Study and Therapeutics |
| title_fullStr | Strategies of LncRNA DLX6-AS1 on Study and Therapeutics |
| title_full_unstemmed | Strategies of LncRNA DLX6-AS1 on Study and Therapeutics |
| title_short | Strategies of LncRNA DLX6-AS1 on Study and Therapeutics |
| title_sort | strategies of lncrna dlx6 as1 on study and therapeutics |
| topic | lncRNA DLX6-AS1 regulatory mechanism tumor novel research methodologies therapeutic strategies |
| url | https://www.frontiersin.org/articles/10.3389/fgene.2022.871988/full |
| work_keys_str_mv | AT yanyanzhao strategiesoflncrnadlx6as1onstudyandtherapeutics AT peili strategiesoflncrnadlx6as1onstudyandtherapeutics |