First Report on the Lipid Profile Late after Kawasaki Disease in Iranian Children
Background: Concerns have been raised about the possibility of a predisposition of Kawasaki disease (KD) to abnormal lipid profile after an acute phase of disease, which can predispose them to premature atherosclerosis later in life. We determined the lipid profile of children late after KD, and com...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | International Journal of Preventive Medicine |
| Subjects: | |
| Online Access: | http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2014;volume=5;issue=7;spage=820;epage=824;aulast=Mostafavi |
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| author | Seyyed-Naserredin Mostafavi Elham Barzegar Nayereh Siyah Manssori Roya Kelishadi |
| author_facet | Seyyed-Naserredin Mostafavi Elham Barzegar Nayereh Siyah Manssori Roya Kelishadi |
| author_sort | Seyyed-Naserredin Mostafavi |
| collection | DOAJ |
| description | Background: Concerns have been raised about the possibility of a predisposition of Kawasaki disease (KD) to abnormal lipid profile after an acute phase of disease, which can predispose them to premature atherosclerosis later in life. We determined the lipid profile of children late after KD, and compared it with controls.
Methods: This historical cohort was conducted on 32 subjects: 16 children with history of uncomplicated KD (age 11.8 ± 3.3 years, interval from the initial episode 7.1 years), and 16 healthy age-matched of their sibling or cousins. Fasting serum total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG) levels were compared between groups. In addition, blood pressure and body mass index (BMI) were measured and compared.
Results: Six out of 16 KD patients and 7 out of 16 controls had abnormal lipid values. No significant difference was found in mean values of systolic blood pressures, diastolic blood pressures, BMI, TG, TC, HDL-C, and LDL-C between cases and controls.
Conclusions: We conclude that although Iranian KD children probably had no different lipid profile compared with controls, but due to finding dyslipidemia in more than one-third of KD subjects, we suggest that periodic control of lipid values in these patients is of crucial importance. |
| first_indexed | 2024-12-13T01:24:02Z |
| format | Article |
| id | doaj.art-e7630fee12064eafb088d4719ef0c0a3 |
| institution | Directory Open Access Journal |
| issn | 2008-7802 2008-8213 |
| language | English |
| last_indexed | 2024-12-13T01:24:02Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | International Journal of Preventive Medicine |
| spelling | doaj.art-e7630fee12064eafb088d4719ef0c0a32022-12-22T00:04:11ZengWolters Kluwer Medknow PublicationsInternational Journal of Preventive Medicine2008-78022008-82132014-01-0157820824First Report on the Lipid Profile Late after Kawasaki Disease in Iranian ChildrenSeyyed-Naserredin MostafaviElham BarzegarNayereh Siyah ManssoriRoya KelishadiBackground: Concerns have been raised about the possibility of a predisposition of Kawasaki disease (KD) to abnormal lipid profile after an acute phase of disease, which can predispose them to premature atherosclerosis later in life. We determined the lipid profile of children late after KD, and compared it with controls. Methods: This historical cohort was conducted on 32 subjects: 16 children with history of uncomplicated KD (age 11.8 ± 3.3 years, interval from the initial episode 7.1 years), and 16 healthy age-matched of their sibling or cousins. Fasting serum total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG) levels were compared between groups. In addition, blood pressure and body mass index (BMI) were measured and compared. Results: Six out of 16 KD patients and 7 out of 16 controls had abnormal lipid values. No significant difference was found in mean values of systolic blood pressures, diastolic blood pressures, BMI, TG, TC, HDL-C, and LDL-C between cases and controls. Conclusions: We conclude that although Iranian KD children probably had no different lipid profile compared with controls, but due to finding dyslipidemia in more than one-third of KD subjects, we suggest that periodic control of lipid values in these patients is of crucial importance.http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2014;volume=5;issue=7;spage=820;epage=824;aulast=MostafaviAtherosclerosischildrenIranKawasaki diseaselipid profile |
| spellingShingle | Seyyed-Naserredin Mostafavi Elham Barzegar Nayereh Siyah Manssori Roya Kelishadi First Report on the Lipid Profile Late after Kawasaki Disease in Iranian Children International Journal of Preventive Medicine Atherosclerosis children Iran Kawasaki disease lipid profile |
| title | First Report on the Lipid Profile Late after Kawasaki Disease in Iranian Children |
| title_full | First Report on the Lipid Profile Late after Kawasaki Disease in Iranian Children |
| title_fullStr | First Report on the Lipid Profile Late after Kawasaki Disease in Iranian Children |
| title_full_unstemmed | First Report on the Lipid Profile Late after Kawasaki Disease in Iranian Children |
| title_short | First Report on the Lipid Profile Late after Kawasaki Disease in Iranian Children |
| title_sort | first report on the lipid profile late after kawasaki disease in iranian children |
| topic | Atherosclerosis children Iran Kawasaki disease lipid profile |
| url | http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2014;volume=5;issue=7;spage=820;epage=824;aulast=Mostafavi |
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