TRPV1 in chronic pruritus and pain: Soft modulation as a therapeutic strategy
Chronic pain and pruritus are highly disabling pathologies that still lack appropriate therapeutic intervention. At cellular level the transduction and transmission of pain and pruritogenic signals are closely intertwined, negatively modulating each other. The molecular and cellular pathways involve...
Main Authors: | Asia Fernández-Carvajal, Gregorio Fernández-Ballester, Antonio Ferrer-Montiel |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-09-01
|
Series: | Frontiers in Molecular Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fnmol.2022.930964/full |
Similar Items
-
New Strategies to Develop Novel Pain Therapies: Addressing Thermoreceptors from Different Points of View
by: Antonio Ferrer-Montiel, et al.
Published: (2011-12-01) -
Progress in the Structural Basis of thermoTRP Channel Polymodal Gating
by: Gregorio Fernández-Ballester, et al.
Published: (2023-01-01) -
Molecular mechanisms of pruritus in prurigo nodularis
by: Yixin Shao, et al.
Published: (2023-11-01) -
TRPV1: Structure, Endogenous Agonists, and Mechanisms
by: Miguel Benítez-Angeles, et al.
Published: (2020-05-01) -
Thermo-Transient Receptor Potential Channels: Therapeutic Potential in Gastric Cancer
by: Gang-Fan Zong, et al.
Published: (2022-12-01)