Nornicotine-typed insecticides: The potential insecticides with strong activity against Diaphorina citri
Nicotine and nornicotine-typed compounds are well-known for its potential as insecticide. Some researches have shown that nicotine was highly toxic to Diaphorina citri Kuwayama, an invasive and fast spreading pest. Here we report the effects of nornicotine-typed insecticide against D. citri. Novel c...
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2023-06-01
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| Series: | Advanced Agrochem |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2773237123000266 |
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| author | Pengfei Hu Xiaoping Ye Xiaoping Song Mingxin Yang Yunsheng Zhong Yijing Cen Yanxin Zhang Yiming Song Qingchao Liu |
| author_facet | Pengfei Hu Xiaoping Ye Xiaoping Song Mingxin Yang Yunsheng Zhong Yijing Cen Yanxin Zhang Yiming Song Qingchao Liu |
| author_sort | Pengfei Hu |
| collection | DOAJ |
| description | Nicotine and nornicotine-typed compounds are well-known for its potential as insecticide. Some researches have shown that nicotine was highly toxic to Diaphorina citri Kuwayama, an invasive and fast spreading pest. Here we report the effects of nornicotine-typed insecticide against D. citri. Novel compounds A1-A8, B1–B28, C1–C18 and D1-D12 were synthesized by reported procedure. And bioassays indicated that some of these compounds exhibited good effects against D. citri. Compounds B2, B3, B8, B12, B13, B22, C5, C7, D5, and D9 exhibited the mortality up to 100% within 120 h in 50 mg/L. And further data shows that A2-5, A7, B1, B8, B20 and B22 showed rapid insecticidal activities against D. citri in 24 h with the low LC50 (LC50 < 50 mg/L in 24 h, and LC50 < 30 mg/L in 72 h). Nornicotine-typed derivatives exhibited activity against D. citri, and B8 and B22 exhibited the best insecticidal activity with an LC50 of 18.0 ± 1.0, 18.2 ± 0.9 mg/L in 24 h, which had the lower cost than nicotine and showed the potential as powerful insecticides. |
| first_indexed | 2024-04-24T16:48:56Z |
| format | Article |
| id | doaj.art-e766a95937274f9ab962b2dc5d02db2b |
| institution | Directory Open Access Journal |
| issn | 2773-2371 |
| language | English |
| last_indexed | 2024-04-24T16:48:56Z |
| publishDate | 2023-06-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Advanced Agrochem |
| spelling | doaj.art-e766a95937274f9ab962b2dc5d02db2b2024-03-29T05:51:39ZengKeAi Communications Co., Ltd.Advanced Agrochem2773-23712023-06-0122180184Nornicotine-typed insecticides: The potential insecticides with strong activity against Diaphorina citriPengfei Hu0Xiaoping Ye1Xiaoping Song2Mingxin Yang3Yunsheng Zhong4Yijing Cen5Yanxin Zhang6Yiming Song7Qingchao Liu8College of Chemical Engineering, Department of Pharmaceutical Engineering, Northwest University, 229 Taibai North Road, Xi'an, 710069, ChinaCollege of Chemical Engineering, Department of Pharmaceutical Engineering, Northwest University, 229 Taibai North Road, Xi'an, 710069, ChinaCollege of Chemical Engineering, Department of Pharmaceutical Engineering, Northwest University, 229 Taibai North Road, Xi'an, 710069, ChinaCollege of Chemical Engineering, Department of Pharmaceutical Engineering, Northwest University, 229 Taibai North Road, Xi'an, 710069, ChinaLaboratory of Insect Ecology, South China Agricultural University, Guangzhou, ChinaLaboratory of Insect Ecology, South China Agricultural University, Guangzhou, ChinaCollege of Chemical Engineering, Department of Pharmaceutical Engineering, Northwest University, 229 Taibai North Road, Xi'an, 710069, China; Glycobiology and Glycotechnology Research Center, College of Food Science and Technology, Northwest University, 229 Taibai North Road, Xi'an, 710069, China; College of Life Sciences, Northwest University, 229 Taibai North Road, Xi'an, 710069, China; Corresponding author. College of Chemical Engineering, Department of Pharmaceutical Engineering, Northwest University, 229 Taibai North Road, Xi'an, 710069, China.College of Chemical Engineering, Department of Pharmaceutical Engineering, Northwest University, 229 Taibai North Road, Xi'an, 710069, China; Corresponding author.College of Chemical Engineering, Department of Pharmaceutical Engineering, Northwest University, 229 Taibai North Road, Xi'an, 710069, China; Corresponding author.Nicotine and nornicotine-typed compounds are well-known for its potential as insecticide. Some researches have shown that nicotine was highly toxic to Diaphorina citri Kuwayama, an invasive and fast spreading pest. Here we report the effects of nornicotine-typed insecticide against D. citri. Novel compounds A1-A8, B1–B28, C1–C18 and D1-D12 were synthesized by reported procedure. And bioassays indicated that some of these compounds exhibited good effects against D. citri. Compounds B2, B3, B8, B12, B13, B22, C5, C7, D5, and D9 exhibited the mortality up to 100% within 120 h in 50 mg/L. And further data shows that A2-5, A7, B1, B8, B20 and B22 showed rapid insecticidal activities against D. citri in 24 h with the low LC50 (LC50 < 50 mg/L in 24 h, and LC50 < 30 mg/L in 72 h). Nornicotine-typed derivatives exhibited activity against D. citri, and B8 and B22 exhibited the best insecticidal activity with an LC50 of 18.0 ± 1.0, 18.2 ± 0.9 mg/L in 24 h, which had the lower cost than nicotine and showed the potential as powerful insecticides.http://www.sciencedirect.com/science/article/pii/S2773237123000266Nornicotine-typed compoundsNicotineInsecticideDiaphorina citri KuwayamaSynthesis |
| spellingShingle | Pengfei Hu Xiaoping Ye Xiaoping Song Mingxin Yang Yunsheng Zhong Yijing Cen Yanxin Zhang Yiming Song Qingchao Liu Nornicotine-typed insecticides: The potential insecticides with strong activity against Diaphorina citri Advanced Agrochem Nornicotine-typed compounds Nicotine Insecticide Diaphorina citri Kuwayama Synthesis |
| title | Nornicotine-typed insecticides: The potential insecticides with strong activity against Diaphorina citri |
| title_full | Nornicotine-typed insecticides: The potential insecticides with strong activity against Diaphorina citri |
| title_fullStr | Nornicotine-typed insecticides: The potential insecticides with strong activity against Diaphorina citri |
| title_full_unstemmed | Nornicotine-typed insecticides: The potential insecticides with strong activity against Diaphorina citri |
| title_short | Nornicotine-typed insecticides: The potential insecticides with strong activity against Diaphorina citri |
| title_sort | nornicotine typed insecticides the potential insecticides with strong activity against diaphorina citri |
| topic | Nornicotine-typed compounds Nicotine Insecticide Diaphorina citri Kuwayama Synthesis |
| url | http://www.sciencedirect.com/science/article/pii/S2773237123000266 |
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