Cheminformatic Profiling and Hit Prioritization of Natural Products with Activities against Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA)

Cheminformatic Profiling and Hit Prioritization of Natural Products with Activities against Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA)

Several natural products (NPs) have displayed varying in vitro activities against methicillin-resistant <i>Staphylococcus aureus</i> (MRSA). However, few of these compounds have not been developed into potential antimicrobial drug candidates. This may be due to the high cost and tedious...

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Bibliographic Details
Main Authors: Samson O. Oselusi, Samuel A. Egieyeh, Alan Christoffels
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
cheminformatics
profiling
natural products
methicillin-resistant <i>Staphylococcus aureus</i> (MRSA), hit prioritization
hit-to-lead optimization
drug-likeness
Online Access:https://www.mdpi.com/1420-3049/26/12/3674

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