Rapid transcriptional responses to serum exposure are associated with sensitivity and resistance to antibody-mediated complement killing in invasive Salmonella Typhimurium ST313 [version 1; peer review: 2 approved]
Background: Salmonella Typhimurium ST313 exhibits signatures of adaptation to invasive human infection, including higher resistance to humoral immune responses than gastrointestinal isolates. Full resistance to antibody-mediated complement killing (serum resistance) among nontyphoidal Salmonellae is...
Main Authors: | Edna M. Ondari, Elizabeth J. Klemm, Chisomo L. Msefula, Moataz Abd El Ghany, Jennifer N. Heath, Derek J. Pickard, Lars Barquist, Gordon Dougan, Robert A. Kingsley, Calman A. MacLennan |
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Format: | Article |
Language: | English |
Published: |
Wellcome
2019-04-01
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Series: | Wellcome Open Research |
Online Access: | https://wellcomeopenresearch.org/articles/4-74/v1 |
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